Journal
CURRENT OPINION IN PEDIATRICS
Volume 31, Issue 4, Pages 531-536Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MOP.0000000000000779
Keywords
growth failure; hypoglycemia; micropenis
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Purpose of review This review summarizes pituitary function, and the clinical presentation and treatment of hypopituitarism. Recent findings Updates in the field include new guidelines and meta-analyses on the diagnosis and treatment of select hormone deficiencies, novel treatment options, and advances in next generation sequencing technology. Summary Hypopituitarism is defined as partial or complete loss of a single or multiple pituitary hormones. The clinical presentation of hypopituitarism varies depending on the number and severity of hormone deficiencies. Treatment involves the physiologic replacement of the individual end-organ hormone deficiencies and requires close lifelong monitoring.
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