False-Positive 68Ga-DOTATATE PET/CT in Active Chronic Prostatitis

A 66-year-old man with neuroendocrine tumor originating from midgut was referred to Ga-68-DOTATATE PET/CT imaging for restaging postoperatively. No suspicious uptake regarding residual primary tumoral involvement was seen. But there was diffuse high uptake in prostate gland suggestive of prostatitis or secondary primary tumoral lesion. Concurrent prostate-specific antigen level was 5.02 ng/mL (range, 0-4 ng/mL), C-reactive protein level was 8.25 mg/L (range, <5 mg/L), and white blood cell count was 6.83 x 10(3)/mu L (range, 3.9-10.9 x 10(3)/mu L). Diagnosis of active chronic prostatitis was achieved by core biopsy, which is identified as potential cause for false-positive diffuse uptake on Ga-68-DOTATATE PET/CT.