Journal
CHEMSUSCHEM
Volume 12, Issue 13, Pages 2955-2969Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cssc.201900151
Keywords
homogeneous catalysis; C-H activation; organic synthesis; ligand effects; transition metals
Funding
- National Natural Science Foundation of China [21702019] Funding Source: Medline
- Directorate for Mathematical and Physical Sciences [CHE-1350541] Funding Source: Medline
Ask authors/readers for more resources
Transition metal-catalyzed C-H bond functionalization is among the most efficient and powerful strategies in synthetic organic chemistry to derivatize otherwise inert sites of organic molecules for the construction of C-C and C-heteroatom bonds. However, additional steps are often required to install the directing groups to realize selective C-H bond functionalization of the substrates. These tedious steps run counter to the step-economical nature of the C-H activation. In contrast, direct functionalization of the substrate by using transient ligands avoids the unnecessary steps for the pre-functionalization of the substrates. This Minireview provides a short overview of the major progress made in this field for C-H functionalization at sp(2) and sp(3) carbon centers with different transient working modes, including covalent, hydrogen, and ionic bonds.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available