Journal
CHEMISTRY-A EUROPEAN JOURNAL
Volume 25, Issue 35, Pages 8225-8228Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201900932
Keywords
aldehydes; organocatalysis; photochemistry; thioesters
Categories
Funding
- NSF [CHE-1903983]
- ACS-PRF [57164-ND1]
Ask authors/readers for more resources
A metal- and oxidant-free catalytic method for accessing structurally diverse thioesters from readily accessible, widespread aldehydes, is described. A strategy of a simple organic 9,10-phenanthrenequinone-promoted hydrogen atom transfer (HAT) with visible light was successfully implemented to selectively generate acyl radicals without inducing crossover reactivity of thioester products. The preparative power of the method was demonstrated by broad substrate scope and wide functional group tolerance, and enabled the late-stage modification of complex structures, which are difficult to achieve with the existing protocols.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available