Journal
CHEMISTRY-A EUROPEAN JOURNAL
Volume 25, Issue 35, Pages 8240-8244Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201901397
Keywords
amino acids; C-C bond formation; donor-acceptor systems; traceless acceptors; visible light
Categories
Funding
- Alexander von Humboldt Foundation
- Deutsche Forschungsgemeinschaft [SFB 858]
- Fonds der Chemischen Industrie
Ask authors/readers for more resources
The development and application of traceless acceptor groups in photochemical C-C bond formation is described. This strategy was enabled by the photoexcitation of electron donor-acceptor (EDA) complexes with visible light. The traceless acceptors, which were readily prepared from amino acid and peptide feedstocks, could be used to alkylate a wide range of heteroarene and enamine donors under metal- and peroxide-free conditions. The crucial role of the EDA complexes in the mechanism of these reactions was explored through combined experimental and computational studies.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available