Journal
CHEMISTRY OF HETEROCYCLIC COMPOUNDS
Volume 55, Issue 4-5, Pages 386-391Publisher
SPRINGER
DOI: 10.1007/s10593-019-02469-7
Keywords
3-aminopyrazin-2(1H)-one; 2-halophenylethanone; imidazo[1; 2-a]pyrazin-8(7H)-one; 3-methoxypyrazin-2(1H)-one; pyrazine-2; 3-dione; cyclization
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A suitable approach to the synthesis of 7-arylimidazo[1,2-a]pyrazin-8(7H)-ones starting from esters of oxalic acid monoamides via cyclization of intermediate 3-aminopyrazin-2-ones with -halocarbonyl compounds has been suggested.
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