Journal
CELL STEM CELL
Volume 24, Issue 5, Pages 690-705Publisher
CELL PRESS
DOI: 10.1016/j.stem.2019.03.023
Keywords
-
Categories
Funding
- NIH [MH117459-01, T32MH065214]
Ask authors/readers for more resources
In the adult mammalian hippocampus, new neurons arise from stem and progenitor cell division, in a process known as adult neurogenesis. Adult-generated neurons are sensitive to experience and may participate in hippocampal functions, including learning and memory, anxiety and stress regulation, and social behavior. Increasing evidence emphasizes the importance of new neuron connectivity within hippocampal circuitry for understanding the impact of adult neurogenesis on brain function. In this Review, we discuss how the functional consequences of new neurons arise from the collective interactions of presynaptic and postsynaptic neurons, glial cells, and the extracellular matrix, which together form the tetrapartite synapse.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available