Journal
CARDIOVASCULAR TOXICOLOGY
Volume 19, Issue 5, Pages 474-481Publisher
HUMANA PRESS INC
DOI: 10.1007/s12012-019-09513-0
Keywords
Aluminum phosphide; Phosphine; Poisoning; Cardiotoxicity; Cardiogenic shock; Intraaortic balloon pump
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The mortality rate from aluminum phosphide (AlP) poisoning is as high as 70-100%, with refractory hypotension and severe metabolic acidosis being the two most common presentations in this poisoning. As this poisoning has no specific antidote, treatments revolve around supportive care. Cardiogenic shock created by toxic myocarditis is considered the main cause of mortality in these patients. Meanwhile, the intra-aortic balloon pump (IABP) has been suggested for the treatment of cardiogenic shock. This article reports the successful treatment of cardiogenic shock caused by AlP poisoning in a 17-year-old man and a 21-year-old woman using the IABP procedure.
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