Related references
Note: Only part of the references are listed.Autophagy and its role in gastric cancer
Yijing Cao et al.
CLINICA CHIMICA ACTA (2019)
Autophagy and disease
Andrew Thorburn
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
An Interplay between Senescence, Apoptosis and Autophagy in Glioblastoma Multiforme-Role in Pathogenesis and Therapeutic Perspective
Elzbieta Pawlowska et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells
Mara Vinci et al.
NATURE MEDICINE (2018)
Dysfunctional autophagy following exposure to pro-inflammatory cytokines contributes to pancreatic β-cell apoptosis
Martine Lambelet et al.
CELL DEATH & DISEASE (2018)
SNAP23 regulates BAX-dependent adipocyte programmed cell death independently of canonical macroautophagy
Daorong Feng et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Genes involved in the regulation of different types of autophagy and their participation in cancer pathogenesis
Martyna Bednarczyk et al.
Oncotarget (2018)
mTOR signalling and cellular metabolism are mutual determinants in cancer
Dirk Mossmann et al.
NATURE REVIEWS CANCER (2018)
The therapeutic potential of targeting the PI3K pathway in pediatric brain tumors
Hazel A. Rogers et al.
ONCOTARGET (2017)
Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors
Jean M. Mulcahy Levy et al.
ELIFE (2017)
Potential New Therapies for Pediatric Diffuse Intrinsic Pontine Glioma
Wenyong Long et al.
FRONTIERS IN PHARMACOLOGY (2017)
Autophagy and the Cell Cycle: A Complex Landscape
Sos Gronbaek Mathiassen et al.
FRONTIERS IN ONCOLOGY (2017)
Metabolic Reprogramming in Glioma
Marie Strickland et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2017)
Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma
Alan Mackay et al.
CANCER CELL (2017)
Unraveling the regulation of mTORC2 using logical modeling
Kirsten Thobe et al.
CELL COMMUNICATION AND SIGNALING (2017)
Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathways
Qichao Huang et al.
AUTOPHAGY (2016)
Epigenetic and transcriptional regulation of autophagy
Hi-Jai R. Shin et al.
AUTOPHAGY (2016)
Chloroquine, an autophagy inhibitor, potentiates the radiosensitivity of glioma initiating cells by inhibiting autophagy and activating apoptosis
Hongxing Ye et al.
BMC NEUROLOGY (2016)
Therapeutic interactions of autophagy with radiation and temozolomide in glioblastoma: evidence and issues to resolve
Michael I. Koukourakis et al.
BRITISH JOURNAL OF CANCER (2016)
Targeted Inhibition of Rictor/mTORC2 in Cancer Treatment: A New Era after Rapamycin
Zhipeng Zou et al.
CURRENT CANCER DRUG TARGETS (2016)
Targeting autophagy to sensitive glioma to temozolomide treatment
Yuanliang Yan et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2016)
Suppression of RAF/MEK or PI3K synergizes cytotoxicity of receptor tyrosine kinase inhibitors in glioma tumor-initiating cells
Takashi Shingu et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2016)
Diagnostic and clinical relevance of the autophago-lysosomal network in human gliomas
Lukas Jennewein et al.
ONCOTARGET (2016)
DNA Damage Response and Autophagy: A Meaningful Partnership
Aristides G. Eliopoulos et al.
FRONTIERS IN GENETICS (2016)
DNA damage and the balance between survival and death in cancer biology
Wynand P. Roos et al.
NATURE REVIEWS CANCER (2016)
Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes
David Castel et al.
ACTA NEUROPATHOLOGICA (2015)
Divergent roles of BECN1 in LC3 lipidation and autophagosomal function
Ruina He et al.
AUTOPHAGY (2015)
Dual Targeting of the Autophagic Regulatory Circuitry in Gliomas with Repurposed Drugs Elicits Cell-Lethal Autophagy and Therapeutic Benefit
Ksenya Shchors et al.
CANCER CELL (2015)
Blockage of Autophagy in C6 Glioma Cells Enhanced Radiosensitivity Possibly by Attenuating DNA-PK-Dependent DSB Due to Limited Ku Nuclear Translocation and DNA Binding
C. Liu et al.
CURRENT MOLECULAR MEDICINE (2015)
Drugging PI3K in cancer: refining targets and therapeutic strategies
Timothy A. Yap et al.
CURRENT OPINION IN PHARMACOLOGY (2015)
Overcoming the blood-brain tumor barrier for effective glioblastoma treatment
O. van Tellingen et al.
DRUG RESISTANCE UPDATES (2015)
Recent insights into cell death and autophagy
Brent E. Fitzwalter et al.
FEBS JOURNAL (2015)
Autophagy in DNA Damage Response
Piotr Czarny et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)
Inhibition of autophagy using 3-methyladenine increases cisplatin-induced apoptosis by increasing endoplasmic reticulum stress in U251 human glioma cells
Ruijian Zhang et al.
MOLECULAR MEDICINE REPORTS (2015)
Autophagy at the crossroads of catabolism and anabolism
Jasvinder Kaur et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2015)
TR-14 * A FEASIBILITY AND RANDOMIZED PHASE II STUDY OF VORINOSTAT, BEVACIZUMAB, OR TEMOZOLOMIDE DURING RADIATION FOLLOWED BY MAINTENANCE CHEMOTHERAPY IN NEWLY-DIAGNOSED PEDIATRIC HIGH-GRADE GLIOMA: CHILDREN'S ONCOLOGY GROUP STUDY ACNS0822
L. M. Hoffman et al.
NEURO-ONCOLOGY (2015)
Promotion of Proapoptotic Signals by Lysosomal Photodamage
David Kessel et al.
PHOTOCHEMISTRY AND PHOTOBIOLOGY (2015)
Targeting Autophagy in BRAF-Mutant Tumors
Andrew Thorburn et al.
CANCER DISCOVERY (2015)
Molecular Biology in Pediatric High-Grade Glioma: Impact on Prognosis and Treatment
Daniela Rizzo et al.
BIOMED RESEARCH INTERNATIONAL (2015)
Autosis and autophagic cell death: the dark side of autophagy
Y. Liu et al.
CELL DEATH AND DIFFERENTIATION (2015)
A Phase I Study of Cixutumumab (IMC-A12) in Combination with Temsirolimus (CCI-779) in Children with Recurrent Solid Tumors: AChildren's Oncology Group Phase I Consortium Report
Maryam Fouladi et al.
CLINICAL CANCER RESEARCH (2015)
PI3K/AKT signaling pathway and cancer: an updated review
Miriam Martini et al.
ANNALS OF MEDICINE (2014)
Using BRAFV600E as a marker of autophagy dependence in pediatric brain tumors
Jean M. Mulcahy Levy et al.
AUTOPHAGY (2014)
Autophagy and lysosomal related protein expression patterns in human glioblastoma
Alexandra Giatromanolaki et al.
CANCER BIOLOGY & THERAPY (2014)
To Be or Not to Be? How Selective Autophagy and Cell Death Govern Cell Fate
Douglas R. Green et al.
CELL (2014)
EGFR signaling and autophagy dependence for growth, survival, and therapy resistance
Barry Jutten et al.
CELL CYCLE (2014)
Chaperone-mediated autophagy: roles in disease and aging
Ana Maria Cuervo et al.
CELL RESEARCH (2014)
The role of cell signalling in the crosstalk between autophagy and apoptosis
Laurence A. Booth et al.
CELLULAR SIGNALLING (2014)
Targeting DNA-PKcs and telomerase in brain tumour cells
Resham Lal Gurung et al.
MOLECULAR CANCER (2014)
The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma
Gang Wu et al.
NATURE GENETICS (2014)
PI3K and cancer: lessons, challenges and opportunities
David A. Fruman et al.
NATURE REVIEWS DRUG DISCOVERY (2014)
The return of the nucleus: transcriptional and epigenetic control of autophagy
Jens Fullgrabe et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
Self-consumption: the interplay of autophagy and apoptosis
Guillermo Marino et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
BRAF-V600E mutation in pediatric and adult glioblastoma
Sonika Dahiya et al.
NEURO-ONCOLOGY (2014)
CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2007-2011
Quinn T. Ostrom et al.
NEURO-ONCOLOGY (2014)
Phase I Study of Vinblastine and Sirolimus in Pediatric Patients With Recurrent or Refractory Solid Tumors
Daniel A. Morgenstern et al.
PEDIATRIC BLOOD & CANCER (2014)
IHC Profiler: An Open Source Plugin for the Quantitative Evaluation and Automated Scoring of Immunohistochemistry Images of Human Tissue Samples
Frency Varghese et al.
PLOS ONE (2014)
The Genetic Signatures of Pediatric High-Grade Glioma: No Longer a One-Act Play
Alexander K. Diaz et al.
SEMINARS IN RADIATION ONCOLOGY (2014)
Autophagy promotes paclitaxel resistance of cervical cancer cells: involvement of Warburg effect activated hypoxia-induced factor 1-α-mediated signaling
X. Peng et al.
CELL DEATH & DISEASE (2014)
Unique genetic and epigenetic mechanisms driving paediatric diffuse high-grade glioma
Chris Jones et al.
NATURE REVIEWS CANCER (2014)
Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge
Dominik Sturm et al.
NATURE REVIEWS CANCER (2014)
Regulation of PIK3C3/VPS34 complexes by MTOR in nutrient stress-induced autophagy
Hai-Xin Yuan et al.
AUTOPHAGY (2013)
Autophagy inhibition induces enhanced proapoptotic effects of ZD6474 in glioblastoma
J. Shen et al.
BRITISH JOURNAL OF CANCER (2013)
Epigenetic Regulation of Autophagy by the Methyltransferase G9a
Amaia Artal-Martinez de Narvajas et al.
MOLECULAR AND CELLULAR BIOLOGY (2013)
ATG7 deficiency suppresses apoptosis and cell death induced by lysosomal photodamage
David H. Kessel et al.
AUTOPHAGY (2012)
Hypoxia-Induced Autophagy Promotes Tumor Cell Survival and Adaptation to Antiangiogenic Treatment in Glioblastoma
Yu-Long Hu et al.
CANCER RESEARCH (2012)
mTOR Signaling in Growth Control and Disease
Mathieu Laplante et al.
CELL (2012)
Microautophagy: lesser-known self-eating
Wen-wen Li et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2012)
Targeting EGFR for Treatment of Glioblastoma: Molecular Basis to Overcome Resistance
T. E. Taylor et al.
CURRENT CANCER DRUG TARGETS (2012)
Phase II trial of temsirolimus in children with high-grade glioma, neuroblastoma and rhabdomyosarcoma
Birgit Geoerger et al.
EUROPEAN JOURNAL OF CANCER (2012)
The mTOR Signalling Pathway in Human Cancer
Helena Populo et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2012)
Long-Term Follow-Up of Children Treated for High-Grade Gliomas: Children's Oncology Group L991 Final Study Report
Stephen Alan Sands et al.
JOURNAL OF CLINICAL ONCOLOGY (2012)
Modulation of pediatric brain tumor autophagy and chemosensitivity
Jean M. Mulcahy Levy et al.
JOURNAL OF NEURO-ONCOLOGY (2012)
Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks
Sebastian Alers et al.
MOLECULAR AND CELLULAR BIOLOGY (2012)
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
Jeremy Schwartzentruber et al.
NATURE (2012)
Comprehensive genomic characterization of squamous cell lung cancers
Peter S. Hammerman et al.
NATURE (2012)
Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas
Gang Wu et al.
NATURE GENETICS (2012)
Paediatric and adult malignant glioma: close relatives or distant cousins?
Chris Jones et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2012)
The functions and regulation of the PTEN tumour suppressor
Min Sup Song et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
PTEN promoter methylation and activation of the PI3K/Akt/mTOR pathway in pediatric gliomas and influence on clinical outcome
Sabine Mueller et al.
NEURO-ONCOLOGY (2012)
Mesenchymal Transition and PDGFRA Amplification/Mutation Are Key Distinct Oncogenic Events in Pediatric Diffuse Intrinsic Pontine Gliomas
Stephanie Puget et al.
PLOS ONE (2012)
Chaperone-mediated autophagy: a unique way to enter the lysosome world
Susmita Kaushik et al.
TRENDS IN CELL BIOLOGY (2012)
Pediatric high grade glioma: a review and update on tumor clinical characteristics and biology
Jason Fangusaro
FRONTIERS IN ONCOLOGY (2012)
A Lipid Kinase Cousin Cooperates to Promote Cancer
Brandon Beagle et al.
CANCER CELL (2011)
Phase I Study of Temsirolimus in Pediatric Patients With Recurrent/Refractory Solid Tumors
Sheri L. Spunt et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
Treatment of children with recurrent high grade gliomas with a bevacizumab containing regimen
Chintan Parekh et al.
JOURNAL OF NEURO-ONCOLOGY (2011)
The Role of Autophagy in Cancer: Therapeutic Implications
Zhineng J. Yang et al.
MOLECULAR CANCER THERAPEUTICS (2011)
DNA damage and autophagy
Humberto Rodriguez-Rocha et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2011)
HDACs link the DNA damage response, processing of double-strand breaks and autophagy
Thomas Robert et al.
NATURE (2011)
Integrated genomic analyses of ovarian carcinoma
D. Bell et al.
NATURE (2011)
Cell death assays for drug discovery
Oliver Kepp et al.
NATURE REVIEWS DRUG DISCOVERY (2011)
Mechanisms of mitophagy
Richard J. Youle et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2011)
Treatment of high-grade glioma in children and adolescents
T. J. MacDonald et al.
NEURO-ONCOLOGY (2011)
Temozolomide in the treatment of high-grade gliomas in children: a report from the Children's Oncology Group
Kenneth J. Cohen et al.
NEURO-ONCOLOGY (2011)
Ammonia-induced autophagy is independent of ULK1/ULK2 kinases
Heesun Cheong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
DNA-PKCS binding to p53 on the p21WAF1/CIP1 promoter blocks transcription resulting in cell death
Richard Hill et al.
ONCOTARGET (2011)
Autophagy as a trigger for cell death Autophagic degradation of inhibitor of apoptosis dBruce controls DNA fragmentation during late oogenesis in Drosophila
Ioannis P. Nezis et al.
AUTOPHAGY (2010)
Autophagic degradation of active caspase-8 A crosstalk mechanism between autophagy and apoptosis
Wen Hou et al.
AUTOPHAGY (2010)
A Distinct Spectrum of Copy Number Aberrations in Pediatric High-Grade Gliomas
Dorine A. Bax et al.
CLINICAL CANCER RESEARCH (2010)
Mammalian autophagy: core molecular machinery and signaling regulation
Zhifen Yang et al.
CURRENT OPINION IN CELL BIOLOGY (2010)
Primary postoperative chemotherapy without radiotherapy for treatment of brain tumours other than ependymoma in children under 3 years: Results of the first UKCCSG/SIOP CNS 9204 trial
R. G. Grundy et al.
EUROPEAN JOURNAL OF CANCER (2010)
mTOR regulation of autophagy
Chang Hwa Jung et al.
FEBS LETTERS (2010)
Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis
Ioannis P. Nezis et al.
JOURNAL OF CELL BIOLOGY (2010)
Whole-Genome Profiling of Pediatric Diffuse Intrinsic Pontine Gliomas Highlights Platelet-Derived Growth Factor Receptor α and Poly (ADP-ribose) Polymerase As Potential Therapeutic Targets
Maryam Zarghooni et al.
JOURNAL OF CLINICAL ONCOLOGY (2010)
Lack of Efficacy of Bevacizumab Plus Irinotecan in Children With Recurrent Malignant Glioma and Diffuse Brainstem Glioma: A Pediatric Brain Tumor Consortium Study
Sridharan Gururangan et al.
JOURNAL OF CLINICAL ONCOLOGY (2010)
Integrated Molecular Genetic Profiling of Pediatric High-Grade Gliomas Reveals Key Differences With the Adult Disease
Barbara S. Paugh et al.
JOURNAL OF CLINICAL ONCOLOGY (2010)
The emerging mechanisms of isoform-specific PI3K signalling
Bart Vanhaesebroeck et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Bevacizumab in recurrent high-grade pediatric gliomas
Ashwatha Narayana et al.
NEURO-ONCOLOGY (2010)
The role of autophagy in sensitizing malignant glioma cells to radiation therapy
Wenzhuo Zhuang et al.
ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2009)
PTEN and the PI3-Kinase Pathway in Cancer
Nader Chalhoub et al.
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2009)
Autophagy-driven cell fate decision maker Activated microglia induce specific death of glioma cells by a blockade of basal autophagic flux and secondary apoptosis/necrosis
Rodrigo Mora et al.
AUTOPHAGY (2009)
PARP-1 is involved in autophagy induced by DNA damage
Jose Antonio Munoz-Gomez et al.
AUTOPHAGY (2009)
EGFRvIII Deletion Mutations in Pediatric High-Grade Glioma and Response to Targeted Therapy in Pediatric Glioma Cell Lines
Dorine A. Bax et al.
CLINICAL CANCER RESEARCH (2009)
Emerging common themes in regulation of PIKKs and PI3Ks
Harri Lempiaeinen et al.
EMBO JOURNAL (2009)
AMPK-mediated autophagy inhibits apoptosis in cisplatin-treated tumour cells
L. Harhaji-Trajkovic et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2009)
The DNA-damage response in human biology and disease
Stephen P. Jackson et al.
NATURE (2009)
Targeting the phosphoinositide 3-kinase pathway in cancer
Pixu Liu et al.
NATURE REVIEWS DRUG DISCOVERY (2009)
Antiangiogenic therapies for high-grade glioma
Andrew D. Norden et al.
NATURE REVIEWS NEUROLOGY (2009)
Molecular and Phenotypic Characterisation of Paediatric Glioma Cell Lines as Models for Preclinical Drug Development
Dorine A. Bax et al.
PLOS ONE (2009)
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
Daniel J. Klionsky et al.
AUTOPHAGY (2008)
Diffuse brainstem gliomas in children: should we or shouldn't we biopsy?
Darren Hargrave
BRITISH JOURNAL OF NEUROSURGERY (2008)
Survival of cancer cells is maintained by EGFR independent of its kinase activity
Zhang Weihua et al.
CANCER CELL (2008)
Hypoxia signals autophagy in tumor cells via AMPK activity, independent of HIF-1, BNIP3, and BNIP3L
I. Papandreou et al.
CELL DEATH AND DIFFERENTIATION (2008)
DNA-damage repair; the good, the bad, and the ugly
Razqallah Hakem
EMBO JOURNAL (2008)
Treatment of Pediatric Brain Tumors
Matthias Karajannis et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2008)
IGFBP2 Is Overexpressed by Pediatric Malignant Astrocytomas and Induces the Repair Enzyme DNA-PK
Oren J. Becher et al.
JOURNAL OF CHILD NEUROLOGY (2008)
Chemotherapy for Malignant Brain Tumors of Childhood
Nicholas G. Gottardo et al.
JOURNAL OF CHILD NEUROLOGY (2008)
Tyrosine kinase expression in pediatric high grade astrocytoma
Muh-Lii Liang et al.
JOURNAL OF NEURO-ONCOLOGY (2008)
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
L. Chin et al.
NATURE (2008)
Class IPI3K in oncogenic cellular transformation
L. Zhao et al.
ONCOGENE (2008)
An oncogene-induced DNA damage model for cancer development
Thanos D. Halazonetis et al.
SCIENCE (2008)
The DNA damage response: Ten years after
J. Wade Harper et al.
MOLECULAR CELL (2007)
High-grade astrocytoma in very young children
Robert P. Sanders et al.
PEDIATRIC BLOOD & CANCER (2007)
MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma
Andrew M. Donson et al.
PEDIATRIC BLOOD & CANCER (2007)
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
Shideng Bao et al.
NATURE (2006)
Rarity of PTEN deletions and EGFR amplification in malignant gliomas of childhood:: results from the Children's Cancer Group 945 cohort
Ian F. Pollack et al.
JOURNAL OF NEUROSURGERY (2006)
PIK3CA gene mutations in pediatric and adult glioblastoma multiforme
Gary L. Gallia et al.
MOLECULAR CANCER RESEARCH (2006)
Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis
M Cully et al.
NATURE REVIEWS CANCER (2006)
Oncogenic PI3K and its role in cancer
Y Samuels et al.
CURRENT OPINION IN ONCOLOGY (2006)
Exploiting the PI3K/AKT pathway for cancer drug discovery
BT Hennessy et al.
NATURE REVIEWS DRUG DISCOVERY (2005)
Inhibition of the DNA-dependent protein kinase catalytic subunit radiosensitizes malignant gliorna cells by inducing autophagy
S Daido et al.
CANCER RESEARCH (2005)
Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors
H Takeuchi et al.
CANCER RESEARCH (2005)
MGMT gene silencing and benefit from temozolomide in glioblastoma
ME Hegi et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Mutation analysis of B-RAF gene in human gliomas
D Basto et al.
ACTA NEUROPATHOLOGICA (2005)
DNA damage-induced apoptosis requires the DNA-dependent protein kinase, and is mediated by the latent population of p53
RA Woo et al.
EMBO JOURNAL (2002)