Electrochemical Determination of Bisphenol A in Saliva by a Novel Three-Dimensional (3D) Printed Gold-Reduced Graphene Oxide (rGO) Composite Paste Electrode

A novel synthesized gold (Au)-reduced graphene oxide composite (rGO) was used for the fabrication of an electroactive paste inserted in a three-dimensional (3D)-printed platform for the determination of bisphenol A (BPA). The proposed method exhibits good response towards oxidation of BPA in the linear concentration range from 1.00 x 10(-7) mol L-1 to 1.00 x 10(-2) mol L-1. The Au-rGO based 3D-printed platform determined BPA with a detection limit of 3.52 x 10(-9) mol L-1, in comparison with rGO based 3D-printed platform, where the limit of detection was 3.05 x 10(-6) mol L-1. Gold modification of rGO improves the sensitivity and electrochemical behavior of the material for BPA oxidation. The method was validated using five saliva samples collected from children.