Related references
Note: Only part of the references are listed.N-Alkyl-α-amino acids in Nature and their biocatalytic preparation
Julia F. Hyslop et al.
JOURNAL OF BIOTECHNOLOGY (2019)
Biomimetic cofactors and methods for their recycling
Ioannis Zachos et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2019)
Alternative coenzymes for biocatalysis
Alice Guarneri et al.
CURRENT OPINION IN BIOTECHNOLOGY (2019)
The fourth wave of biocatalysis is approaching
Uwe T. Bornscheuer
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES (2018)
Highly Productive Oxidative Biocatalysis in Continuous Flow by Enhancing the Aqueous Equilibrium Solubility of Oxygen
Michael R. Chapman et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)
Complete Switch of Reaction Specificity of an Aldolase by Directed Evolution In Vitro: Synthesis of Generic Aliphatic Aldol Products
Sebastian Junker et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)
Nucleophile Promiscuity of Engineered ClassII Pyruvate Aldolase YfaU from E.Coli
Karel Hernandez et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)
Biocatalysis for the synthesis of pharmaceuticals and pharmaceutical intermediates
Huihua Sun et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2018)
Identification of Novel Bacterial Members of the Imine Reductase Enzyme Family that Perform Reductive Amination
Scott P. France et al.
CHEMCATCHEM (2018)
Application of Threonine Aldolases for the Asymmetric Synthesis of α-Quaternary α-Amino Acids
Julia Blesl et al.
CHEMCATCHEM (2018)
The limits to biocatalysis: pushing the envelope
Roger A. Sheldon et al.
CHEMICAL COMMUNICATIONS (2018)
Transaminases for chiral amine synthesis
Andrew Gomm et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2018)
Synthesis of chiral amines using redox biocatalysis
Gideon Grogan
CURRENT OPINION IN CHEMICAL BIOLOGY (2018)
Enzymatic amidation for industrial applications
Brent M. Dorr et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2018)
Application of Smart Amine Donors for Rapid Screening and Scale-Up of Transaminase-Mediated Biotransformations
Andrew Gomm et al.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2018)
A versatile biosynthetic approach to amide bond formation
Helena K. Philpott et al.
GREEN CHEMISTRY (2018)
Identification and Implementation of Biocatalytic Transformations in Route Discovery: Synthesis of Chiral 1,3-Substituted Cyclohexanone Building Blocks
Timin Hadi et al.
ORGANIC PROCESS RESEARCH & DEVELOPMENT (2018)
Selective Synthesis of the Human Drug Metabolite 5′-Hydroxypropranolol by an Evolved Self-Sufficient Peroxygenase
Patricia Gomez de Santos et al.
ACS CATALYSIS (2018)
The Broad Aryl Acid Specificity of the Amide Bond Synthetase McbA Suggests Potential for the Biocatalytic Synthesis of Amides
Mark Petchey et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)
Biocatalytic Synthesis of Chiral N-Functionalized Amino Acids
Julia F. Hyslop et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)
Synthesis of 2,5-Disubstituted Pyrrolidine Alkaloids via A One-Pot Cascade Using Transaminase and Reductive Aminase Biocatalysts
Bruna Z. Costa et al.
CHEMCATCHEM (2018)
Biomimetic synthesis of 2-substituted N-heterocycle alkaloids by one-pot hydrolysis, transamination and decarboxylative Mannich reaction
James L. Galman et al.
CHEMICAL COMMUNICATIONS (2018)
Progress in using threonine aldolases for preparative synthesis
Sarah F. Beaudoin et al.
ENZYME AND MICROBIAL TECHNOLOGY (2018)
Biocatalysis in Drug Development-Highlights of the Recent Patent Literature
David L. Hughes
ORGANIC PROCESS RESEARCH & DEVELOPMENT (2018)
Biocatalytic Aldol Addition of Simple Aliphatic Nucleophiles to Hydroxyaldehydes
Raquel Roldan et al.
ACS CATALYSIS (2018)
Amide Synthesis via Aminolysis of Ester or Acid with an Intracellular Lipase
Shichao Zeng et al.
ACS CATALYSIS (2018)
A Mechanism for Reductive Amination Catalyzed by Fungal Reductive Aminases
Mahima Sharma et al.
ACS CATALYSIS (2018)
Role of Biocatalysis in Sustainable Chemistry
Roger A. Sheldon et al.
CHEMICAL REVIEWS (2018)
Development of Halogenase Enzymes for Use in Synthesis
Jonathan Latham et al.
CHEMICAL REVIEWS (2018)
Biocatalytic transamination with near-stoichiometric inexpensive amine donors mediated by bifunctional mono- and di-amine transaminases
James L. Galman et al.
GREEN CHEMISTRY (2017)
Structures of carboxylic acid reductase reveal domain dynamics underlying catalysis
Deepankar Gahloth et al.
NATURE CHEMICAL BIOLOGY (2017)
A reductive aminase from Aspergillus oryzae
Godwin A. Aleku et al.
NATURE CHEMISTRY (2017)
A Chemoenzymatic Route to Chiral Intermediates Used in the Multikilogram Synthesis of a Gamma Secretase Inhibitor
Michael Burns et al.
ORGANIC PROCESS RESEARCH & DEVELOPMENT (2017)
Biocatalysis in the Pharmaceutical Industry: The Need for Speed
Matthew D. Truppo
ACS MEDICINAL CHEMISTRY LETTERS (2017)
Understanding and Overcoming the Limitations of Bacillus badius and Caldalkalibacillus thermarum Amine Dehydrogenases for Biocatalytic Reductive Amination
Ahir Pushpanath et al.
ACS CATALYSIS (2017)
Efficient Biocatalytic Reductive Aminations by Extending the Imine Reductase Toolbox
Gheorghe-Doru Roiban et al.
CHEMCATCHEM (2017)
Selective Activation of C-H Bonds in a Cascade Process Combining Photochemistry and Biocatalysis
Wuyuan Zhang et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)
Biocatalytic Routes to Enantiomerically Enriched Dibenz[c,e]azepines
Scott P. France et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)
Breaking the Dogma of Aldolase Specificity: Simple Aliphatic Ketones and Aldehydes are Nucleophiles for Fructose-6-phosphate Aldolase
Raquel Roldan et al.
CHEMISTRY-A EUROPEAN JOURNAL (2017)
Recent advances in methyltransferase biocatalysis
Matthew R. Bennett et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2017)
Enzymatic Biocatalysis in Chemical Synthesis of Pharmaceuticals (Review)
A. M. Bezborodov et al.
APPLIED BIOCHEMISTRY AND MICROBIOLOGY (2016)
Nonclassical Routes for Amide Bond Formation
Renata Marcia de Figueiredo et al.
CHEMICAL REVIEWS (2016)
A New Generation of Smart Amine Donors for Transaminase-Mediated Biotransformations
Andrew Gomm et al.
CHEMISTRY-A EUROPEAN JOURNAL (2016)
Highly engineered biocatalysts for efficient small molecule pharmaceutical synthesis
Jim Lalonde
CURRENT OPINION IN BIOTECHNOLOGY (2016)
Sustainable synthesis of enantiopure fluorolactam derivatives by a selective direct fluorination - amidase strategy
Nicky J. Willis et al.
GREEN CHEMISTRY (2016)
Transaminase Triggered Aza-Michael Approach for the Enantioselective Synthesis of Piperidine Scaffolds
James Ryan et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)
Enabling Selective and Sustainable P450 Oxygenation Technology. Production of 4-Hydroxy-α-isophorone on Kilogram Scale
Iwona Kaluzna et al.
ORGANIC PROCESS RESEARCH & DEVELOPMENT (2016)
Identification of imine reductase-specific sequence motifs
Silvia Fademrecht et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2016)
Minimalist Protein Engineering of an Aldolase Provokes Unprecedented Substrate Promiscuity
Deniz Gueclue et al.
ACS CATALYSIS (2016)
Stereoselectivity and Structural Characterization of an Irvine Reductase (IRED) from Amycolatopsis orientalis
Godwin A. Aleku et al.
ACS CATALYSIS (2016)
Asymmetric Reductive Amination of Ketones Catalyzed by Imine Reductases
Dennis Wetzl et al.
CHEMCATCHEM (2016)
Structure, Activity and Stereoselectivity of NADPH-Dependent Oxidoreductases Catalysing the S-Selective Reduction of the Imine Substrate 2-Methylpyrroline
Henry Man et al.
CHEMBIOCHEM (2015)
Expanding the Imine Reductase Toolbox by Exploring the Bacterial Protein-Sequence Space
Dennis Wetzl et al.
CHEMBIOCHEM (2015)
A Practical and Fast Method To Predict the Thermodynamic Preference of ω-Transaminase-Based Transformations
Robert J. Meier et al.
CHEMCATCHEM (2015)
Imine Reductase-Catalyzed Intermolecular Reductive Amination of Aldehydes and Ketones
Philipp N. Scheller et al.
CHEMCATCHEM (2015)
A Model to Assess the Feasibility of Shifting Reaction Equilibrium by Acetone Removal in the Transamination of Ketones Using 2-propylamine
Par Tufvesson et al.
BIOTECHNOLOGY AND BIOENGINEERING (2014)
Regioselective Biocatalytic Aromatic Hydroxylation in a Gas-Liquid Multiphase Tube-in-Tube Reactor
Bartlomiej Tomaszewski et al.
CHEMCATCHEM (2014)
Direct Reductive Amination of Ketones: Structure and Activity of S-Selective Imine Reductases from Streptomyces
Tobias Huber et al.
CHEMCATCHEM (2014)
Nitrilase Activity Screening on Structurally Diverse Substrates: Providing Biocatalytic Tools for Organic Synthesis
Carine Vergne-Vaxelaire et al.
ADVANCED SYNTHESIS & CATALYSIS (2013)
A NADPH-dependent (S)-imine reductase (SIR) from Streptomyces sp GF3546 for asymmetric synthesis of optically active amines: purification, characterization, gene cloning, and expression
Koichi Mitsukura et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2013)
Structure and Activity of NADPH-Dependent Reductase Q1EQE0 from Streptomyces kanamyceticus, which Catalyses the R-Selective Reduction of an Imine Substrate
Maria Rodriguez-Mata et al.
CHEMBIOCHEM (2013)
Estimation of the size of drug-like chemical space based on GDB-17 data
P. G. Polishchuk et al.
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2013)
Development of an Amine Dehydrogenase for Synthesis of Chiral Amines
Michael J. Abrahamson et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)
Experimental determination of thermodynamic equilibrium in biocatalytic transamination
Par Tufvesson et al.
BIOTECHNOLOGY AND BIOENGINEERING (2012)
Engineering the third wave of biocatalysis
U. T. Bornscheuer et al.
NATURE (2012)
Cytochrome P450-catalyzed L-tryptophan nitration in thaxtomin phytotoxin biosynthesis
Sarah M. Barry et al.
NATURE CHEMICAL BIOLOGY (2012)
Purification and Characterization of a Novel (R)-Imine Reductase from Streptomyces sp GF3587
Koichi Mitsukura et al.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2011)
Peptide Coupling Reagents, More than a Letter Soup
Ayman El-Faham et al.
CHEMICAL REVIEWS (2011)
Cytochromes P450: exploiting diversity and enabling application as biocatalysts
Gideon Grogan
CURRENT OPINION IN CHEMICAL BIOLOGY (2011)
Enzymatic reductions for the chemist
Frank Hollmann et al.
GREEN CHEMISTRY (2011)
Pseudomonas stutzeri lipase: a useful biocatalyst for aminolysis reactions
S. van Pelt et al.
GREEN CHEMISTRY (2011)
Highlights of Transition Metal-Catalyzed Asymmetric Hydrogenation of Imines
Nicolas Fleury-Bregeot et al.
CHEMCATCHEM (2010)
Practical chiral alcohol manufacture using ketoreductases
Gjalt W. Huisman et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2010)
Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture
Christopher K. Savile et al.
SCIENCE (2010)
Amide bond formation: beyond the myth of coupling reagents
Eric Valeur et al.
CHEMICAL SOCIETY REVIEWS (2009)
Key green chemistry research areas - a perspective from pharmaceutical manufacturers
David J. C. Constable et al.
GREEN CHEMISTRY (2007)
Cloning and optimization of a nitrilase for the synthesis of (3S)-3-cyano-5-methyl hexanoic acid
Zhiyi Xie et al.
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC (2006)
Nitrilase-catalysed desymmetrisation of 3-hydroxyglutaronitrile: Preparation of a statin side-chain intermediate
Sophie Bergeron et al.
ORGANIC PROCESS RESEARCH & DEVELOPMENT (2006)
Preparation of human metabolites of propranolol using laboratory-evolved bacterial cytochromes P450
CR Otey et al.
BIOTECHNOLOGY AND BIOENGINEERING (2006)
Analysis of the reactions used for the preparation of drug candidate molecules
John S. Carey et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2006)
Development of an efficient, scalable, aldolase-catalyzed process for enantioselective synthesis of statin intermediates
WA Greenberg et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Novel haloperoxidase from the agaric basidiomycete Agrocybe aegerita oxidizes aryl alcohols and aldehydes
R Ulrich et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2004)
(E)-selective hydrolysis of (E,Z)-α,β-unsaturated nitriles by the recombinant nitrilase AtNIT1 from Arabidopsis thaliana
F Effenberger et al.
TETRAHEDRON-ASYMMETRY (2001)
Share Paper
