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Small nanobody drugs win big backing from pharma
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Preoperative lymphocyte count is a favorable prognostic factor of disease-free survival in non-small-cell lung cancer
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Impact of GLUT1 and Ki-67 expression on early-stage lung adenocarcinoma diagnosed according to a new international multidisciplinary classification
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Eicosanoid Profiling in an Orthotopic Model of Lung Cancer Progression by Mass Spectrometry Demonstrates Selective Production of Leukotrienes by Inflammatory Cells of the Microenvironment
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PLOS ONE (2013)
Emergence of spatial structure in the tumor microenvironment due to the Warburg effect
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Role of c-MYC in tumor-associated macrophages and cancer progression
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Role of Macrophage Migration Inhibitory Factor in the Regulatory T Cell Response of Tumor-Bearing Mice
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Systemic Analysis of PPARγ in Mouse Macrophage Populations Reveals Marked Diversity in Expression with Critical Roles in Resolution of Inflammation and Airway Immunity
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A Small-Molecule Inhibitor of Glucose Transporter 1 Downregulates Glycolysis, Induces Cell-Cycle Arrest, and Inhibits Cancer Cell Growth In Vitro and In Vivo
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Preoperative lymphocyte count is an independent prognostic factor in node-negative non-small cell lung cancer
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Inflammasomes in carcinogenesis and anticancer immune responses
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NATURE IMMUNOLOGY (2012)
Origins of tumor-associated macrophages and neutrophils
Virna Cortez-Retamozo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells
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Macrophages and Tissue Injury: Agents of Defense or Destruction?
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ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 51, 2011 (2011)
Lung Cancer Signatures in Plasma Based on Proteome Profiling of Mouse Tumor Models
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Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche
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Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study
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CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis
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Adipose Triglyceride Lipase Contributes to Cancer-Associated Cachexia
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CD40 Agonists Alter Tumor Stroma and Show Efficacy Against Pancreatic Carcinoma in Mice and Humans
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Charles A. Dinarello
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Immunity, Inflammation, and Cancer
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CURRENT OPINION IN IMMUNOLOGY (2010)
IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion
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Hypoxia-inducible factor 2α regulates macrophage function in mouse models of acute and tumor inflammation
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Targeted PPARγ deficiency in alveolar macrophages disrupts surfactant catabolism
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Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm
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Novel alternatively spliced ADAM8 isoforms contribute to the aggressive bone metastatic phenotype of lung cancer
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PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
How the Noninflammasome NLRs Function in the Innate Immune System
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SCIENCE (2010)
Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
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The polarization of immune cells in the tumour environment by TGFβ
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Macrophage death and defective inflammation resolution in atherosclerosis
Ira Tabas
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Promotion of Lung Carcinogenesis by Chronic Obstructive Pulmonary Disease-Like Airway Inflammation in a K-ras-Induced Mouse Model
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A distinguishing gene signature shared by tumor-infiltrating Tie2-expressing monocytes, blood resident monocytes, and embryonic macrophages suggests common functions and developmental relationships
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CD4+ T Cells Regulate Pulmonary Metastasis of Mammary Carcinomas by Enhancing Protumor Properties of Macrophages
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PLOS ONE (2009)
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
Matthew G. Vander Heiden et al.
SCIENCE (2009)
Epithelial-mesenchymal transition: At the crossroads of development and tumor metastasis
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Suzanne L. Cassel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
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SCIENCE (2008)
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David M. Mosser et al.
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The role of myeloid cells in the promotion of tumour angiogenesis
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Tie2-expressing monocytes: regulation of tumor angiogenesis and therapeutic implications
Michele De Palma et al.
TRENDS IN IMMUNOLOGY (2007)
CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature
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Targeting CCL2 with systemic delivery of neutralizing antibodies induces prostate cancer tumor regression in vivo
Robert D. Loberg et al.
CANCER RESEARCH (2007)
Direct visualization of macrophage-assisted tumor cell intravasation in mammary tumors
Jeffrey B. Wyckoff et al.
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Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment
Hua Yu et al.
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Interleukin-1 and cancer progression: the emerging role of interleukin-1 receptor antagonist as a novel therapeutic agent in cancer treatment
Anne M. Lewis et al.
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Acute effect of cigarette smoke on TNF-α release by macrophages mediated through the erk1/2 pathway
Loutfig Demirjian et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2006)
Alveolar macrophage function is altered in patients with lung cancer
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The involvement of IL-1 in tumorigenesis, tumor invasiveness, metastasis and tumor-host interactions
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Monocyte and macrophage heterogeneity
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Infiltration of COX-2-expressing macrophages is a prerequisite for IL-1β-induced neovascularization and tumor growth
S Nakao et al.
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The stromal derived factor-1/CXCL12-CXC chemokine receptor 4 biological axis in non-small cell lung cancer metastases
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IL-1 is required for tumor invasiveness and angiogenesis
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Proinflammatory cytokine IL-1β promotes tumor growth of Lewis lung carcinoma by induction of angiogenic factors:: In vivo analysis of tumor-stromal interaction
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Acute cigarette smoke exposure induces apoptosis of alveolar macrophages
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