Related references
Note: Only part of the references are listed.Heterogeneity of Thyroid Function and Impact of Peripheral Thyroxine Deiodination in Centenarians and Semi-Supercentenarians: Association With Functional Status and Mortality
Rita Ostan et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2019)
Adipokine dysregulation and adipose tissue inflammation in human obesity
Xabier Unamuno et al.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2018)
Nutrition and Inflammation: Are Centenarians Similar to Individuals on Calorie-Restricted Diets?
Claudio Franceschi et al.
ANNUAL REVIEW OF NUTRITION, VOL 38 (2018)
Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice
Kai Mao et al.
NATURE COMMUNICATIONS (2018)
Frailty and Associated Factors among Centenarians in the 5-COOP Countries
Marie Herr et al.
GERONTOLOGY (2018)
A Long-lived Mouse Lacking Both Growth Hormone and Growth Hormone Receptor: A New Animal Model for Aging Studies
Adam Gesing et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2017)
Insulin Receptor Isoforms in Physiology and Disease: An Updated View
Antonino Belfiore et al.
ENDOCRINE REVIEWS (2017)
Activation-Induced Autophagy Is Preserved in CD4+T-Cells in Familial Longevity
Yotam Raz et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2017)
GH/IGF-I/insulin system in centenarians
Giovanni Vitale et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2017)
Centenarians as a 21st century healthy aging model: A legacy of humanity and the need for a world-wide consortium (WWC100+)
Claudio Franceschi et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2017)
Inflammaging and 'Garb-aging'
Claudio Franceschi et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2017)
The GH receptor exon 3 deletion is a marker of male-specific exceptional longevity associated with increased GH sensitivity and taller stature
Danny Ben-Avraham et al.
SCIENCE ADVANCES (2017)
IGF-1 has sexually dimorphic, pleiotropic, and time-dependent effects on healthspan, pathology, and lifespan
Nicole M. Ashpole et al.
GEROSCIENCE (2017)
Effect of caloric restriction on gut permeability, inflammation markers, and fecal microbiota in obese women
Beate Ott et al.
SCIENTIFIC REPORTS (2017)
THE ENDOCRINOLOGY OF AGING: A KEY TO LONGEVITY GREAT EXPECTATIONS
S. Sethu K. Reddy et al.
ENDOCRINE PRACTICE (2017)
GH and ageing: Pitfalls and new insights
Andrzej Bartke et al.
BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM (2017)
Effects of 2-year calorie restriction on circulating levels of IGF-1, IGF-binding proteins and cortisol in nonobese men and women: a randomized clinical trial
Luigi Fontana et al.
AGING CELL (2016)
BODY COMPOSITION ASSESSMENT AND NUTRITIONAL STATUS EVALUATION IN MEN AND WOMEN PORTUGUESE CENTENARIANS
A. Pereira da Silva et al.
JOURNAL OF NUTRITION HEALTH & AGING (2016)
Growth hormone secretion is diminished and tightly controlled in humans enriched for familial longevity
Evie van der Spoel et al.
AGING CELL (2016)
Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits
Alexander Teumer et al.
AGING CELL (2016)
Effects of dietary restriction on adipose mass and biomarkers of healthy aging in human
Daniele Lettieri-Barbato et al.
AGING-US (2016)
Long-term moderate calorie restriction inhibits inflammation without impairing cell-mediated immunity: a randomized controlled trial in non-obese humans
Simin N. Meydani et al.
AGING-US (2016)
Centenarians' offspring as a model of healthy aging: a reappraisal of the data on Italian subjects and a comprehensive overview
Laura Bucci et al.
AGING-US (2016)
Aging of the endocrine system and its potential impact on sarcopenia
Giovanni Vitale et al.
EUROPEAN JOURNAL OF INTERNAL MEDICINE (2016)
Employing biomarkers of healthy ageing for leveraging genetic studies into human longevity
Joris Deelen et al.
EXPERIMENTAL GERONTOLOGY (2016)
Age and Sex Distributions of Age-Related Biomarker Values in Healthy Older Adults from the Long Life Family Study
Paola Sebastiani et al.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2016)
Association analysis of insulin-like growth factor-1 axis parameters with survival and functional status in nonagenarians of the Leiden Longevity Study
Evie van der Spoel et al.
AGING-US (2015)
Decreased epigenetic age of PBMCs from Italian semi-supercentenarians and their offspring
Steve Horvath et al.
AGING-US (2015)
Thyroid Function Decreases with Age and May Contribute to Longevity in Chinese Centenarians' Families
Yong-Han He et al.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2015)
A 2-Year Randomized Controlled Trial of Human Caloric Restriction: Feasibility and Effects on Predictors of Health Span and Longevity
Eric Ravussin et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2015)
Change in N-Glycosylation of Plasma Proteins in Japanese Semisupercentenarians
Yuri Miura et al.
PLOS ONE (2015)
Longevity effect of IGF-1R+/- mutation depends on genetic background-specific receptor activation
Jie Xu et al.
AGING CELL (2014)
Mitochondria hyperfusion and elevated autophagic activity are key mechanisms for cellular bioenergetic preservation in centenarians
Gianluca Sgarbi et al.
AGING-US (2014)
Regulation of adiponectin multimerization, signaling and function
Meilian Liu et al.
BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM (2014)
Leptin and aging: Review and questions with particular emphasis on its role in the central regulation of energy balance
Marta Balasko et al.
JOURNAL OF CHEMICAL NEUROANATOMY (2014)
Lifespan Modulation in Mice and the Confounding Effects of Genetic Background
Lorna Mulvey et al.
JOURNAL OF GENETICS AND GENOMICS (2014)
The Influence of Shc Proteins on Life Span in Mice
Jon J. Ramsey et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2014)
Can Enhanced Autophagy Be Associated with Human Longevity? Serum Levels of the Autophagy Biomarker Beclin-1 Are Increased in Healthy Centenarians
Enzo Emanuele et al.
REJUVENATION RESEARCH (2014)
Gene set analysis of GWAS data for human longevity highlights the relevance of the insulin/IGF-1 signaling and telomere maintenance pathways
Joris Deelen et al.
AGE (2013)
Role of epigenetics in human aging and longevity: genome-wide DNA methylation profile in centenarians and centenarians' offspring
Davide Gentilini et al.
AGE (2013)
Calorie restriction in humans inhibits the PI3K/AKT pathway and induces a younger transcription profile
Evi M. Mercken et al.
AGING CELL (2013)
Inflamm-ageing
Elisa Cevenini et al.
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2013)
Immune System, Cell Senescence, Aging and Longevity - Inflamm-Aging Reappraised
Stefano Salvioli et al.
CURRENT PHARMACEUTICAL DESIGN (2013)
Role of PAPP-A in aging and age-related disease
Cheryl A. Conover
EXPERIMENTAL GERONTOLOGY (2013)
Assessment of adiponectin and its isoforms in Polish centenarians
Wojciech Bik et al.
EXPERIMENTAL GERONTOLOGY (2013)
Does the longevity of one or both parents influence the health status of their offspring?
P. Gueresi et al.
EXPERIMENTAL GERONTOLOGY (2013)
The GH/IGF-1 axis in ageing and longevity
Riia K. Junnila et al.
NATURE REVIEWS ENDOCRINOLOGY (2013)
Oxidative stress and the ageing endocrine system
Giovanni Vitale et al.
NATURE REVIEWS ENDOCRINOLOGY (2013)
Growth hormone-releasing hormone disruption extends lifespan and regulates response to caloric restriction in mice
Liou Y. Sun et al.
ELIFE (2013)
Low circulating IGF-I bioactivity is associated with human longevity: Findings in centenarians' offspring
Giovanni Vitale et al.
AGING-US (2012)
Peripheral regulation of the growth hormone-insulin-like growth factor system in fish and other vertebrates
Katie M. Reindl et al.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY (2012)
Insulin-Like Growth Factor-1 Physiology: Lessons from Mouse Models
Shoshana Yakar et al.
ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA (2012)
Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study
Julie A. Mattison et al.
NATURE (2012)
Caloric restriction delays aging-induced cellular phenotypes in rhesus monkey skeletal muscle
Susan H. McKiernan et al.
EXPERIMENTAL GERONTOLOGY (2011)
Common adipokine features of neonates and centenarians
Cristina Meazza et al.
JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM (2011)
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
Darren J. Baker et al.
NATURE (2011)
Liver-Derived IGF-I Regulates Mean Life Span in Mice
Johan Svensson et al.
PLOS ONE (2011)
Does Reduced IGF-1R Signaling in Igf1r+/- Mice Alter Aging?
Alex F. Bokov et al.
PLOS ONE (2011)
A cross-section analysis of FT3 age-related changes in a group of old and oldest-old subjects, including centenarians' relatives, shows that a down-regulated thyroid function has a familial component and is related to longevity
Andrea Corsonello et al.
AGE AND AGEING (2010)
The effect of caloric restriction interventions on growth hormone secretion in nonobese men and women
Leanne M. Redman et al.
AGING CELL (2010)
Early life growth hormone treatment shortens longevity and decreases cellular stress resistance in long-lived mutant mice
Jacob A. Panici et al.
FASEB JOURNAL (2010)
IGF-1, oxidative stress and atheroprotection
Yusuke Higashi et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2010)
Human insulin/IGF-1 and familial longevity at middle age
Maarten P. Rozing et al.
AGING-US (2009)
Insulin/IGF-like signalling, the central nervous system and aging
Susan Broughton et al.
BIOCHEMICAL JOURNAL (2009)
Reduced Incidence and Delayed Occurrence of Fatal Neoplastic Diseases in Growth Hormone Receptor/Binding Protein Knockout Mice
Yuji Ikeno et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2009)
Endocrine alterations in response to calorie restriction in humans
Leanne M. Redman et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2009)
The metabolic syndrome, IGF-1, and insulin action
Yasumichi Arai et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2009)
Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys
Ricki J. Colman et al.
SCIENCE (2009)
Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice
Colin Selman et al.
FASEB JOURNAL (2008)
Role of the GH/IGF-1 axis in lifespan and healthspan: Lessons from animal models
Darlene E. Berryman et al.
GROWTH HORMONE & IGF RESEARCH (2008)
Adipose Endocrine Function, Insulin-Like Growth Factor-1 Axis, and Exceptional Survival Beyond 100 Years of Age
Yasurmichi Arai et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2008)
Adiponectin levels and genotype: A potential regulator of life span in humans
Gil Atzmon et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2008)
Functionally significant insulin-like growth factor I receptor mutations in centenarians
Yousin Suh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Loss of pregnancy-associated plasma protein A extends lifespan in mice
Cheryl A. Conover et al.
AGING CELL (2007)
Brain IRS2 signaling coordinates life span and nutrient homeostasis
Akiko Taguchi et al.
SCIENCE (2007)
Calorie restriction or exercise: effects on coronary heart disease risk factors. A randomized, controlled trial
Luigi Fontana et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2007)
Evaluation of neuroendocrine status in longevity
Boguslawa Baranowska et al.
NEUROBIOLOGY OF AGING (2007)
Inflammaging and anti-inflammaging: A systemic perspective on aging and longevity emerged from studies in humans
Claudio Franceschi et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2007)
Family clustering in Sardinian longevity: A genealogical approach
Graziella Caselli et al.
EXPERIMENTAL GERONTOLOGY (2006)
Targeted disruption of growth hormone receptor interferes with the beneficial actions of calorie restriction
Michael S. Bonkowski et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Suppression of aging in mice by the hormone Klotho
H Kurosu et al.
SCIENCE (2005)
Reduced insulin/IGF-1 signalling and human longevity
D van Heemst et al.
AGING CELL (2005)
Tissue-specific activities of C-elegans DAF-16 in the regulation of lifespan
N Libina et al.
CELL (2003)
Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulin-like growth factor I levels and increased life span
KT Coschigano et al.
ENDOCRINOLOGY (2003)
Polymorphic variants of insulin-like growth factor I (IGF-I) receptor and phosphoinositide 3-kinase genes affect IGF-I plasma levels and human longevity:: Cues for an evolutionarily conserved mechanism of life span control
M Bonafè et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2003)
Increased circulating Interleukin-18 levels in centenarians with no signs of vascular disease:: another paradox of longevity?
S Gangemi et al.
EXPERIMENTAL GERONTOLOGY (2003)
IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice
M Holzenberger et al.
NATURE (2003)
Adult-onset calorie restriction and fasting delay spontaneous tumorigenesis in p53-deficient mice
D Berrigan et al.
CARCINOGENESIS (2002)
Low insulin resistance and preserved β-cell function contribute to human longevity but are not associated with TH-INS genes
G Paolisso et al.
EXPERIMENTAL GERONTOLOGY (2001)
Longevity - Extending the lifespan of long-lived mice
A Bartke et al.
NATURE (2001)
Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production
K Flurkey et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein
DJ Clancy et al.
SCIENCE (2001)
A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function
M Tatar et al.
SCIENCE (2001)
Serum insulin-like growth factor-1 in centenarians: Implications of IGF-1 as a rapid turnover protein
Y Arai et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2001)
The network and the remodeling theories of aging:: historical background and new perspectives
C Franceschi et al.
EXPERIMENTAL GERONTOLOGY (2000)
Share Paper
