Journal
SCIENCE CHINA-MATERIALS
Volume 62, Issue 6, Pages 885-891Publisher
SCIENCE PRESS
DOI: 10.1007/s40843-018-9384-8
Keywords
live cells; ZIF-8; viability protection
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Funding
- National Key Basic Research Program of China [2014CB931801, 2016YFA0200700]
- National Natural Science Foundation of China [2189038, 21721002, 21475029]
- Frontier Science Key Project of Chinese Academy of Sciences [QYZDJ-SSW-SLH038]
- K. C. Wong Education Foundation
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In this study, a yeast@ZIF-8 core-shell composite material was successfully synthesized under room temperature in aqueous solution. The ZIF-8 shell endowed the inner yeast cells with a considerably extended lifetime without any nutrients at 4 degrees C. Compared with the bare yeast cells, most coated yeast cells were kept alive even when cultured in zymolyase solution for 3 h. Furthermore, the encapsulated yeast cells could be reactivated and regrown by dissolving the ZIF-8 shell with competitive coordination interactions.
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