4.7 Article Data Paper

Single-cell RNA-seq of cultured human adipose-derived mesenchymal stem cells

Journal

SCIENTIFIC DATA
Volume 6, Issue -, Pages -

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/sdata.2019.31

Keywords

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Funding

  1. National Natural Science Foundation of China [81670444, 81870229]
  2. CAMS Initiative for Innovative Medicine [2016-I2M-1-016]
  3. Post-doctoral International Exchange Project of Peking Union Medical College [2018-BSH04]

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Adipose-derived mesenchymal stem cells (ADSCs) show considerable promise for clinical applications in regenerative medicine. We performed a large-scale single-cell transcriptomic sequencing of 24,358 cultured human ADSCs from three donors. We provide a high-quality dataset, which would be a valuable resource for dissecting the intrapopulation heterogeneity of cultured ADSCs as well as interrogating lineage priming patterns for any interested lineages at single-cell resolution.

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