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Relationship between microglial activation and dopaminergic neuronal loss in the substantia nigra: a time course study in a 6-hydroxydopamine model of Parkinson's disease
Lilia Marinova-Mutafchieva et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Acute and Chronic 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Administrations Elicit Similar Microglial Activation in the Substantia Nigra of Monkeys
Marianne Vazquez-Claverie et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2009)
Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease
Wataru Satake et al.
NATURE GENETICS (2009)
Progressive Dopaminergic Degeneration in the Chronic MPTPp Mouse Model of Parkinson's Disease
Nicoletta Schintu et al.
NEUROTOXICITY RESEARCH (2009)
CXCR4 and CXCL12 Expression is Increased in the Nigro-Striatal System of Parkinson's Disease
Mika Shimoji et al.
NEUROTOXICITY RESEARCH (2009)
Behavior, neurotransmitters and inflammation in three regimens of the MPTP mouse model of Parkinson's disease
Dirk W. Luchtman et al.
PHYSIOLOGY & BEHAVIOR (2009)
Environmental toxins and Parkinson's disease: what have we learned from pesticide-induced animal models?
Francesca Cicchetti et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2009)
Central and systemic IL-1 exacerbates neurodegeneration and motor symptoms in a model of Parkinson's disease
Maria Clara Pott Godoy et al.
BRAIN (2008)
A pilot clinical trial of creatine and minocycline in early Parkinson disease: 18-month results
Karl Kieburtz et al.
CLINICAL NEUROPHARMACOLOGY (2008)
Reactive oxygen species up-regulate CD11b in microglia via nitric oxide: Implications for neurodegenerative diseases
Avik Roy et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
The lipopolysaccharide Parkinson's disease animal model: mechanistic studies and drug discovery
Garima Dutta et al.
FUNDAMENTAL & CLINICAL PHARMACOLOGY (2008)
Multiplex analysis of cytokines in the serum and cerebrospinal fluid of patients with Alzheimer's disease by color-coded bead technology
Chulhee Choi et al.
JOURNAL OF CLINICAL NEUROLOGY (2008)
Decreased blood-brain barrier P-glycoprotein function in the progression of Parkinson's disease, PSP and MSA
A. L. Bartels et al.
JOURNAL OF NEURAL TRANSMISSION (2008)
The effects of MPTP on the activation of microglia/astrocytes and cytokine/chemokine levels in different mice strains
Y. Yasuda et al.
JOURNAL OF NEUROIMMUNOLOGY (2008)
Neuroinflammation mediated by IL-1β increases susceptibility of dopamine neurons to degeneration in an animal model of Parkinson's disease
James B. Koprich et al.
JOURNAL OF NEUROINFLAMMATION (2008)
Targeted Overexpression of Human α-Synuclein Triggers Microglial Activation and an Adaptive Immune Response in a Mouse Model of Parkinson Disease
Shaji Theodore et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2008)
Parkin Deficiency Increases Vulnerability to Inflammation-Related Nigral Degeneration
Tamy C. Frank-Cannon et al.
JOURNAL OF NEUROSCIENCE (2008)
Synuclein activates microglia in a model of Parkinson's disease
Xiaomin Su et al.
NEUROBIOLOGY OF AGING (2008)
The blood-brain barrier in health and chronic neurodegenerative disorders
Berislav V. Zlokovic
NEURON (2008)
Serum interleukin (IL-2, IL-10, IL-6, IL-4), TNFα, and INFγ concentrations are elevated in patients with atypical and idiopathic parkinsonism
Bogdan Brodacki et al.
NEUROSCIENCE LETTERS (2008)
Nitrated α-Synuclein Immunity Accelerates Degeneration of Nigral Dopaminergic Neurons
Eric J. Benner et al.
PLOS ONE (2008)
The exploration of rotenone as a toxin for inducing Parkinson's disease in rats, for application in BBB transport and PK–PD experiments
Paulien G.M. Ravenstijn et al.
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS (2007)
Local self-renewal can sustain CNS microglia maintenance and function throughout adult life
Bahareh Ajami et al.
NATURE NEUROSCIENCE (2007)
Neuroprotective activities of CD4+CD25+ regulatory T cells in an animal model of Parkinson's disease
Ashley D. Reynolds et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2007)
Development of α-synuclein immunoreactive astrocytes in the forebrain parallels stages of intraneuronal pathology in sporadic Parkinson's disease
Heiko Braak et al.
ACTA NEUROPATHOLOGICA (2007)
Long-lasting reactive changes observed in microglia in the striatal and substantia nigral of mice after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Y. Yasuda et al.
BRAIN RESEARCH (2007)
Involvement of interferon-γ in microglial-mediated loss of dopaminergic neurons
Matthew P. Mount et al.
JOURNAL OF NEUROSCIENCE (2007)
Long-term consequences of human alpha-synuclein overexpression in the primate ventral midbrain
Andisheh Eslamboli et al.
BRAIN (2007)
Peripheral inflammation and neuroprotection: Systemic pretreatment with complete Freund's adjuvant reduces 6-hydroxydopamine toxicity in a rodent model of Parkinson's disease
Marie-Therese Armentero et al.
NEUROBIOLOGY OF DISEASE (2006)
Blocking soluble tumor necrosis factor signaling with dominant-negative tumor necrosis factor inhibitor attenuates loss of dopaminergic neurons in models of Parkinson's disease
Melissa K. McCoy et al.
JOURNAL OF NEUROSCIENCE (2006)
Up-regulation of microglial CD11b expression by nitric oxide
Avik Roy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Expression levels of vascular endothelial growth factor and its receptors in Parkinson's disease
Keiichirou Wada et al.
NEUROREPORT (2006)
Role of ICAM-1 in persisting inflammation in Parkinson disease and MPTP monkeys
J Miklossy et al.
EXPERIMENTAL NEUROLOGY (2006)
In vivo imaging of microglial activation with [11C](R)-PK11195 PET in idiopathic Parkinson's disease
A Gerhard et al.
NEUROBIOLOGY OF DISEASE (2006)
LRRK2 G2019S as a cause of Parkinson's disease in North African Arabs
S Lesage et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Nonsteroidal antiinflammatory drug use and the risk for Parkinson's disease
HL Chen et al.
ANNALS OF NEUROLOGY (2005)
Myelin basic protein-primed T cells of female but not male mice induce nitric-oxide synthase and proinflammatory cytokines in microglia - Implications for gender bias in multiple sclerosis
S Dasgupta et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
6-Hydroxydopamine-induced alterations in blood-brain barrier permeability
PM Carvey et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2005)
ATP mediates rapid microglial response to local brain injury in vivo
D Davalos et al.
NATURE NEUROSCIENCE (2005)
Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
A Nimmerjahn et al.
SCIENCE (2005)
The choroid plexus in the rise, fall and repair of the brain
DF Emerich et al.
BIOESSAYS (2005)
Microglial activation and dopamine terminal loss in early Parkinson's disease
Y Ouchi et al.
ANNALS OF NEUROLOGY (2005)
Blood-brain barrier dysfunction in Parkinsonian midbrain in vivo
R Kortekaas et al.
ANNALS OF NEUROLOGY (2005)
Changes in vascularization in substantia nigra pars compacta of monkeys rendered parkinsonian
C Barcia et al.
JOURNAL OF NEURAL TRANSMISSION (2005)
Blood-brain barrier transport of cytokines: A mechanism for neuropathology
WA Banks
CURRENT PHARMACEUTICAL DESIGN (2005)
Distribution of major histocompatibility complex class II-positive microglia and cytokine profile of Parkinson's disease brains
K Imamura et al.
ACTA NEUROPATHOLOGICA (2003)
Microglial activation with atypical proinflammatory cytokine expression in a rat model of Parkinson's disease
AM Depino et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2003)
Role of very-late antigen-4 (VLA-4) in myelin basic protein-primed T cell contact-induced expression of proinflammatory cytokines in microglial cells
S Dasgupta et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Subcutaneous rotenone exposure causes highly selective dopaminergic degeneration and alpha-synuclein aggregation
TB Sherer et al.
EXPERIMENTAL NEUROLOGY (2003)
Presence of reactive microglia in monkey substantia nigra years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration
PL McGeer et al.
ANNALS OF NEUROLOGY (2003)
Mice deficient in TNF receptors are protected against dopaminergic neurotoxicity: Implications for Parkinson's disease
K Sriram et al.
FASEB JOURNAL (2002)
Neuroinflammation of the nigrostriatal pathway during progressive 6-OHDA dopamine degeneration in rats monitored by immunohistochemistry and PET imaging
F Cicchetti et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2002)
Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease
DC Wu et al.
JOURNAL OF NEUROSCIENCE (2002)
RANTES: a versatile and controversial chemokine
V Appay et al.
TRENDS IN IMMUNOLOGY (2001)
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
R Betarbet et al.
NATURE NEUROSCIENCE (2000)