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NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Clusterin Isoforms differentially affect growth and motility of prostate cells: Possible implications in prostate tumorigenesis
Roberta M. Moretti et al.
CANCER RESEARCH (2007)
Multiple pathways regulating the anti-apoptotic protein clusterin in breast cancer
Melissa K. Ranney et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2007)
The extracellular chaperone clusterin influences amyloid formation and toxicity by interacting with prefibrillar structures
Justin J. Yerbury et al.
FASEB JOURNAL (2007)
Epigenetic regulation of clusterin/apolipoprotein J expression in retinal pigment epithelial cells
Tiina Suuronen et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Clusterin expression in normal mucosa and colorectal cancer
Claus Lindbjerg Andersen et al.
MOLECULAR & CELLULAR PROTEOMICS (2007)
Transport pathways for clearance of human Alzheimer's amyloid β-peptide and apolipoproteins E and J in the mouse central nervous system
Robert D. Bell et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2007)
Stress-induced retrotranslocation of clusterin/ApoJ into the cytosol
Philippe Nizard et al.
TRAFFIC (2007)
Identification of epigenetically silenced genes in tumor endothelial cells
Debby M. E. I. Hellebrekers et al.
CANCER RESEARCH (2007)
Aβ oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine
Fernanda G. De Felice et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Regulation of clusterin expression in mammary epithelial cells
Yoko Itahana et al.
EXPERIMENTAL CELL RESEARCH (2007)
Effects of glycosylation on the structure and function of the extracellular chaperone clusterin
Elise M. Stewart et al.
BIOCHEMISTRY (2007)
Amyloid-β 1-42 induced endocytosis and clusterin/apoJ protein accumulation in cultured human astrocytes
Tapio Nuutinen et al.
NEUROCHEMISTRY INTERNATIONAL (2007)
Differential regulation of clusterin and its Isoforms by androgens in prostate cells
Dawn R. Cochrane et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database
Lars Bertram et al.
NATURE GENETICS (2007)
Anticlusterin treatment of breast cancer cells increases the sensitivities of chemotherapy and tamoxifen and counteracts the inhibitory action of dexamethasone on chemotherapy-induced cytotoxicity
Maximino Redondo et al.
BREAST CANCER RESEARCH (2007)
Regulation of clusterin/apolipoprotein J, a functional homologue to the small heat shock proteins, by oxidative stress in ageing and age-related diseases
Ioannis P. Trougakos et al.
FREE RADICAL RESEARCH (2006)
The TREM receptor family and signal integration
Julia Klesney-Tait et al.
NATURE IMMUNOLOGY (2006)
Clusterin up-regulation following sub-lethal oxidative stress and lipid peroxidation in human neuroblastoma cells
Paola Strocchi et al.
NEUROBIOLOGY OF AGING (2006)
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
Michael T. Lin et al.
NATURE (2006)
Gene expression correlates of neurofibrillary tangles in Alzheimer's disease
Travis Dunckley et al.
NEUROBIOLOGY OF AGING (2006)
Clusterin in cerebrospinal fluid:: Analysis of carbohydrates and quantification of native and glycosylated forms
A. -M. Nilselid et al.
NEUROCHEMISTRY INTERNATIONAL (2006)
Sustained astrocytic clusterin expression improves remodeling after brain ischemia
A Imhof et al.
NEUROBIOLOGY OF DISEASE (2006)
Up-regulation of the clusterin gene after proteotoxic stress:: implication of HSF1-HSF2 heterocomplexes
F Loison et al.
BIOCHEMICAL JOURNAL (2006)
Role of genes and environments for explaining Alzheimer disease
M Gatz et al.
ARCHIVES OF GENERAL PSYCHIATRY (2006)
Knockdown of the cytoprotective chaperone, clusterin, chemosensitizes human breast cancer cells both in vitro and in vivo
A So et al.
MOLECULAR CANCER THERAPEUTICS (2005)
Clusterin as a therapeutic target for radiation sensitization in a lung cancer model
C Cao et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2005)
Clusterin interacts with SCLIP (SCG10-like protein) and promotes neurite outgrowth of PC12 cells
SW Kang et al.
EXPERIMENTAL CELL RESEARCH (2005)
A phase I pharmacokinetic and pharmacodynamic study of OGX-011, a 2′-methoxyethyl antisense oligonucleotide to clusterin, in patients with localized prostate cancer
KN Chi et al.
JOURNAL OF THE NATIONAL CANCER INSTITUTE (2005)
Clusterin inhibits apoptosis by interacting with activated Bax
HL Zhang et al.
NATURE CELL BIOLOGY (2005)
A structure-based model of the c-Myc/Bin1 protein interaction shows alternative splicing of Bin1 and c-Myc phosphorylation are key binding determinants
A Pineda-Lucena et al.
JOURNAL OF MOLECULAR BIOLOGY (2005)
Apolipoprotein J (clusterin) activates rodent microglia in vivo and in vitro
Z Xie et al.
JOURNAL OF NEUROCHEMISTRY (2005)
Delayed activation of insulin-like growth factor-1 receptor/Src/MAPK/Egr-1 signaling regulates clusterin expression, a pro-survival factor
T Criswell et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Association of apolipoprotein J-positive beta-amyloid plaques with dystrophic neurites in Alzheimer's disease brain
MD Martin-Rehrmann et al.
NEUROTOXICITY RESEARCH (2005)
Up-regulated expression of cytoplasmic clusterin in human ovarian carcinoma
D Xie et al.
CANCER (2005)
Antisense oligodeoxynucleotide therapy targeting clusterin gene for prostate cancer: Vancouver experience from discovery to clinic
H Miyake et al.
INTERNATIONAL JOURNAL OF UROLOGY (2005)
Modulation of different clusterin isoforms in human colon tumorigenesis
S Pucci et al.
ONCOGENE (2004)
Silencing expression of the clusterin/apolipoprotein J gene in human cancer cells using small interfering RNA induces spontaneous apoptosis, reduced growth ability, and cell sensitization to genotoxic and oxidative stress
IP Trougakos et al.
CANCER RESEARCH (2004)
ApoE and clusterin cooperatively suppress Aβ levels and deposition:: Evidence that ApoE regulates extracellular Aβ metabolism in vivo
RB DeMattos et al.
NEURON (2004)
Intracellular clusterin induces G2-M phase arrest and cell death in PC-3 prostate cancer cells
M Scaltriti et al.
CANCER RESEARCH (2004)
Pathways towards and away from Alzheimer's disease
MP Mattson
NATURE (2004)
What and when of cognitive aging
TA Salthouse
CURRENT DIRECTIONS IN PSYCHOLOGICAL SCIENCE (2004)
The pathophysiology of mitochondrial cell death
DR Green et al.
SCIENCE (2004)
Clusterin overexpression in both malignant and nonmalignant prostate epithelial cells induces cell cycle arrest and apoptosis
M Scaltriti et al.
BRITISH JOURNAL OF CANCER (2004)
Induction of Dickkopf-1, a negative modulator of the Wnt pathway, is associated with neuronal degeneration in Alzheimer's brain
A Caricasole et al.
JOURNAL OF NEUROSCIENCE (2004)
Role of oxidative modifications in atherosclerosis
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PHYSIOLOGICAL REVIEWS (2004)
Essential requirement of apolipoprotein J (clusterin) signaling for IκB expression and regulation of NF-κB activity
G Santilli et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Alterations in the post-translational modification and intracellular trafficking of clusterin in MCF-7 cells during apoptosis
J O'Sullivan et al.
CELL DEATH AND DIFFERENTIATION (2003)
Intracellular clusterin causes juxtanuclear aggregate formation and mitochondrial alteration
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JOURNAL OF CELL SCIENCE (2003)
Central role of the proteasome in senescence and survival of human fibroblasts - Induction of a senescence-like phenotype upon its inhibition and resistance to stress upon its activation
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JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Repression of IR-inducible clusterin expression by the p53 tumor suppressor protein
T Criswell et al.
CANCER BIOLOGY & THERAPY (2003)
Microglial apolipoprotein E and astroglial apolipoprotein J expression in vitro:: opposite effects of lipopolysaccharide
J Saura et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Delayed, but prolonged increases in astrocytic clusterin (ApoJ) mRNA expression following acute cortical spreading depression in the rat: evidence for a role of clusterin in ischemic tolerance
AK Wiggins et al.
MOLECULAR BRAIN RESEARCH (2003)
Synthesis and functional analyses of nuclear clusterin, a cell death protein
KS Leskov et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Role of extracellular HSP72 in acute stress-induced potentiation of innate immunity in active rats
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JOURNAL OF APPLIED PHYSIOLOGY (2003)
ASAP: the Alternative Splicing Annotation Project
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NUCLEIC ACIDS RESEARCH (2003)
Oxidative stress and aging: beyond correlation
TR Golden et al.
AGING CELL (2002)
Signal transduction in H2O2-induced senescence-like phenotype in human diploid fibroblasts
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FREE RADICAL BIOLOGY AND MEDICINE (2002)
Metalloenzyme-like activity of Alzheimer's disease β-amyloid -: Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H2O2
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JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Clusterin/apolipoprotein J is associated with cortical Lewy bodies:: immunohistochemical study in cases with α-synucleinopathies
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ACTA NEUROPATHOLOGICA (2002)
Suppression of clusterin expression enhanced cisplatin-induced cytotoxicity on renal cell carcinoma cells
CH Lee et al.
UROLOGY (2002)
Clusterin promotes amyloid plaque formation and is critical for neuritic toxicity in a mouse model of Alzheimer's disease
RB DeMattos et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Increase of brain oxidative stress in mild cognitive impairment -: A possible predictor of Alzheimer disease
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ARCHIVES OF NEUROLOGY (2002)
Clusterin
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INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2002)
Clusterin expression is significantly enhanced in prostate cancer cells following androgen withdrawal therapy
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PROSTATE (2002)
Increased clusterin (apolipoprotein J) expression in human and mouse brains infected with transmissible spongiform encephalopathies
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ACTA NEUROPATHOLOGICA (2002)
When X-ray-inducible proteins meet DNA double strand break repair
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SEMINARS IN RADIATION ONCOLOGY (2001)
Apolipoprotein J/clusterin is induced in vascular smooth muscle cells after vascular injury
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CIRCULATION (2001)
Inhibition of post-ischemic brain injury by clusterin overexpression
DM Holtzman et al.
NATURE MEDICINE (2001)
Complement activation by neurofibrillary tangles in Alzheimer's disease
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NEUROSCIENCE LETTERS (2001)
Clusterin contributes to caspase-3-independent brain injury following neonatal hypoxia-ischemia
BH Han et al.
NATURE MEDICINE (2001)
Neurotoxic Aβ peptides increase oxidative stress in vivo through NMDA-receptor and nitric-oxide-synthase mechanisms, and inhibit complex IV activity and induce a mitochondrial permeability transition in vitro
JK Parks et al.
JOURNAL OF NEUROCHEMISTRY (2001)
Clusterin is an ATP-independent chaperone with very broad substrate specificity that stabilizes stressed proteins in a folding-competent state
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BIOCHEMISTRY (2000)
Oxidants, oxidative stress and the biology of ageing
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NATURE (2000)
Apolipoprotein J/clusterin limits the severity of murine autoimmune myocarditis
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JOURNAL OF CLINICAL INVESTIGATION (2000)
Evidence that the β-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of Aβ by zinc
MP Cuajungco et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Nuclear clusterin/XIP8, an x-ray-induced Ku70-binding protein that signals cell death
CR Yang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Laminar shear stress upregulates the complement-inhibitory protein clusterin - A novel potent defense mechanism against complement-induced endothelial cell activation
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CIRCULATION (2000)
Clusterin is a secreted mammalian chaperone
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TRENDS IN BIOCHEMICAL SCIENCES (2000)
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