Related references
Note: Only part of the references are listed.Telomere and its role in the aging pathways: telomere shortening, cell senescence and mitochondria dysfunction
Yukun Zhu et al.
BIOGERONTOLOGY (2019)
Chemical screen identifies a geroprotective role of quercetin in premature aging
Lingling Geng et al.
PROTEIN & CELL (2019)
RELN signaling modulates glioblastoma growth and substrate-dependent migration
Markus Schulze et al.
BRAIN PATHOLOGY (2018)
Rap1 deficiency-provoked paracrine dysfunction impairs immunosuppressive potency of mesenchymal stem cells in allograft rejection of heart transplantation
Yue Ding et al.
CELL DEATH & DISEASE (2018)
CRISPR/Cas9-mediated gene knockout reveals a guardian role of NF-B/RelA in maintaining the homeostasis of human vascular cells
Ping Wang et al.
PROTEIN & CELL (2018)
ATF6 safeguards organelle homeostasis and cellular aging in human mesenchymal stem cells
Si Wang et al.
CELL DISCOVERY (2018)
SIRT6 deficiency results in developmental retardation cynomolgus monkeys
Weiqi Zhang et al.
NATURE (2018)
Mice lacking RAP1 show early onset and higher rates of DEN-induced hepatocellular carcinomas in female mice
Lole Ferrara-Romeo et al.
PLOS ONE (2018)
Reelin (RELN) DNA methylation in the peripheral blood of schizophrenia
Rahim Mohd Nabil Fikri et al.
JOURNAL OF PSYCHIATRIC RESEARCH (2017)
A practical qPCR approach to detect TERRA, the elusive telomeric repeat-containing RNA
Marianna Feretzaki et al.
METHODS (2017)
Trypanosoma brucei RAP1 maintains telomere and subtelomere integrity by suppressing TERRA and telomeric RNA: DNA hybrids
Vishal Nanavaty et al.
NUCLEIC ACIDS RESEARCH (2017)
Cytoplasmic RAP1 mediates cisplatin resistance of non-small cell lung cancer
Lu Xiao et al.
CELL DEATH & DISEASE (2017)
Systematic analysis of human telomeric dysfunction using inducible telosome/shelterin CRISPR/Cas9 knockout cells
Hyeung Kim et al.
CELL DISCOVERY (2017)
Genetic enhancement in cultured human adult stem cells conferred by a single nucleotide recoding
Jiping Yang et al.
CELL RESEARCH (2017)
Regulation of Stem Cell Aging by Metabolism and Epigenetics
Ruotong Ren et al.
CELL METABOLISM (2017)
S100A6 protein: functional roles
Rosario Donato et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2017)
The differential spatiotemporal expression pattern of shelterin genes throughout lifespan
Kay-Dietrich Wagner et al.
AGING-US (2017)
Visualization of aging-associated chromatin alterations with an engineered TALE system
Ruotong Ren et al.
CELL RESEARCH (2017)
A genetic interaction between RAP1 and telomerase reveals an unanticipated role for RAP1 in telomere maintenance
Paula Martinez et al.
AGING CELL (2016)
Age intrinsic loss of telomere protection via TRF1 reduction in endothelial cells
P. J. Hohensinner et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2016)
Shelterin Protects Chromosome Ends by Compacting Telomeric Chromatin
Jigar N. Bandaria et al.
CELL (2016)
Repression of the Antioxidant NRF2 Pathway in Premature Aging
Nard Kubben et al.
CELL (2016)
SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2
Huize Pan et al.
CELL RESEARCH (2016)
Shelterin
Isabelle Schmutz et al.
CURRENT BIOLOGY (2016)
Differential methylation at the RELN gene promoter in temporal cortex from autistic and typically developing post-puberal subjects
Carla Lintas et al.
JOURNAL OF NEURODEVELOPMENTAL DISORDERS (2016)
Reelin and Neuropsychiatric Disorders
Kazuhiro Ishii et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2016)
Modeling xeroderma pigmentosum associated neurological pathologies with patients-derived iPSCs
Lina Fu et al.
PROTEIN & CELL (2016)
HISAT: a fast spliced aligner with low memory requirements
Daehwan Kim et al.
NATURE METHODS (2015)
Stem cells and healthy aging
Margaret A. Goodell et al.
SCIENCE (2015)
A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging
Weiqi Zhang et al.
SCIENCE (2015)
Human telomere biology: A contributory and interactive factor in aging, disease risks, and protection
Elizabeth H. Blackburn et al.
SCIENCE (2015)
PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype
Shunlei Duan et al.
NATURE COMMUNICATIONS (2015)
The asymmetry of telomere replication contributes to replicative senescence heterogeneity
Thibault Bourgeron et al.
SCIENTIFIC REPORTS (2015)
Telomere Maintenance Mechanisms in Cancer: Clinical Implications
Roger R. Reddel
CURRENT PHARMACEUTICAL DESIGN (2014)
Generation of cerebral organoids from human pluripotent stem cells
Madeline A. Lancaster et al.
NATURE PROTOCOLS (2014)
How does Reelin control neuronal migration and layer formation in the developing mammalian neocortex?
Katsutoshi Sekine et al.
NEUROSCIENCE RESEARCH (2014)
Downregulation of Rap1 promotes 5-fluorouracil-induced apoptosis in hepatocellular carcinoma cell line HepG2
Yong Zha et al.
ONCOLOGY REPORTS (2014)
Modelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs
Guang-Hui Liu et al.
NATURE COMMUNICATIONS (2014)
TALEN Gene Knockouts Reveal No Requirement for the Conserved Human Shelterin Protein Rap1 in Telomere Protection and Length Regulation
Shaheen Kabir et al.
CELL REPORTS (2014)
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
Michael I. Love et al.
GENOME BIOLOGY (2014)
The Length of the Shortest Telomere as the Major Determinant of the Onset of Replicative Senescence
Zhou Xu et al.
GENETICS (2013)
Cerebral organoids model human brain development and microcephaly
Madeline A. Lancaster et al.
NATURE (2013)
Telomere Dynamics in Mice and Humans
Rodrigo T. Calado et al.
SEMINARS IN HEMATOLOGY (2013)
Pax8 has a critical role in epithelial cell survival and proliferation
T. Di Palma et al.
CELL DEATH & DISEASE (2013)
RAP1 Protects from Obesity through Its Extratelomeric Role Regulating Gene Expression
Paula Martinez et al.
CELL REPORTS (2013)
Interpretation of Genomic Variants Using a Unified Biological Network Approach
Ekta Khurana et al.
PLOS COMPUTATIONAL BIOLOGY (2013)
Integrative analysis of genome-wide loss of heterozygosity and monoallelic expression at nucleotide resolution reveals disrupted pathways in triple-negative breast cancer
Gavin Ha et al.
GENOME RESEARCH (2012)
Fast gapped-read alignment with Bowtie 2
Ben Langmead et al.
NATURE METHODS (2012)
Telomere length regulates TERRA levels through increased trimethylation of telomeric H3K9 and HP1α
Nausica Arnoult et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)
Human telomeric proteins occupy selective interstitial sites
Dong Yang et al.
CELL RESEARCH (2011)
Genome-Wide Analysis of Promoter Methylation Associated with Gene Expression Profile in Pancreatic Adenocarcinoma
Audrey Vincent et al.
CLINICAL CANCER RESEARCH (2011)
Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome
Guang-Hui Liu et al.
NATURE (2011)
Taking apart Rap1 An adaptor protein with telomeric and non-telomeric functions
Shaheen Kabir et al.
CELL CYCLE (2010)
Mammalian Rap1 controls telomere function and gene expression through binding to telomeric and extratelomeric sites
Paula Martinez et al.
NATURE CELL BIOLOGY (2010)
Loss of Rap1 Induces Telomere Recombination in the Absence of NHEJ or a DNA Damage Signal
Agnel Sfeir et al.
SCIENCE (2010)
RAP1 Is Essential for Silencing Telomeric Variant Surface Glycoprotein Genes in Trypanosoma brucei
Xiaofeng Yang et al.
CELL (2009)
The Reelin and GAD67 Promoters Are Activated by Epigenetic Drugs That Facilitate the Disruption of Local Repressor Complexes
Marija Kundakovic et al.
MOLECULAR PHARMACOLOGY (2009)
Protocols to detect senescence-associated beta-galactosidase (SA-beta gal) activity, a biomarker of senescent cells in culture and in vivo
Florence Debacq-Chainiaux et al.
NATURE PROTOCOLS (2009)
ToppGene Suite for gene list enrichment analysis and candidate gene prioritization
Jing Chen et al.
NUCLEIC ACIDS RESEARCH (2009)
How Shelterin Protects Mammalian Telomeres
Wilhelm Palm et al.
ANNUAL REVIEW OF GENETICS (2008)
Genome-wide profiling of methylated promoters in pancreatic adenocarcinoma
Noriyuki Omura et al.
CANCER BIOLOGY & THERAPY (2008)
A rapid micro chromatin immunoprecipitation assay (mu ChIP)
John Arne Dahl et al.
NATURE PROTOCOLS (2008)
The telosome/shelterin complex and its functions
Huawei Xin et al.
GENOME BIOLOGY (2008)
Induced pluripotent stem cell lines derived from human somatic cells
Junying Yu et al.
SCIENCE (2007)
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
Kazutoshi Takahashi et al.
CELL (2007)
Teratoma formation assays with human embryonic stem cells: A rationale for one type of human-animal chimera
M. William Lensch et al.
CELL STEM CELL (2007)
DNA methyltransferase inhibitors coordinately induce expression of the human reelin and glutamic acid decarboxylase 67 genes
Marija Kundakovic et al.
MOLECULAR PHARMACOLOGY (2007)
Differential and epigenetic gene expression profiling identifies frequent disruption of the RELN pathway in pancreatic cancers
N Sato et al.
GASTROENTEROLOGY (2006)
Telomere length heterogeneity and chromosome instability
JA Londoño-Vallejo
CANCER LETTERS (2004)
The human Rap1 protein complex and modulation of telomere length
MS O'Connor et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Regulation of telomerase by telomeric proteins
A Smogorzewska et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2004)
Modelling cellular senescence as a result of telomere state
CJ Proctor et al.
AGING CELL (2003)
Rap1 affects the length and heterogeneity of human telomeres
BB Li et al.
MOLECULAR BIOLOGY OF THE CELL (2003)
Rap1-Sir4 binding independent of other Sir, yKu, or histone interactions initiates the assembly of telomeric heterochromatin in yeast
KH Luo et al.
GENES & DEVELOPMENT (2002)
Telomere measurement by quantitative PCR
RM Cawthon
NUCLEIC ACIDS RESEARCH (2002)
Systematic identification of novel protein domain families associated with nuclear functions
T Doerks et al.
GENOME RESEARCH (2002)
Multiple interactions in sir protein recruitment by Rap1p at silencers and telomeres in yeast
P Moretti et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
spRap1 and spRif1, recruited to telomeres by Taz1, are essential for telomere function in fission yeast
J Kanoh et al.
CURRENT BIOLOGY (2001)
Switching and signaling at the telomere
EH Blackburn
CELL (2001)
Share Paper
