Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 55, Issue 25, Pages 7227-7230Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201603235
Keywords
amides; carbonylation; copper catalysis; cycloalkanes; imides
Categories
Funding
- Chinese Scholarship Council
- NSFC [21472174]
- Zhejiang Natural Science Fund for Distinguished Young Scholars [LR16B020002]
Ask authors/readers for more resources
Carbonylation reactions are a most powerful method for the synthesis of carbonyl-containing compounds. However, most known carbonylation procedures still require noble-metal catalysts and the use of activated compounds and good nucleophiles as substrates. Herein, we developed a copper-catalyzed carbonylative transformation of cycloalkanes and amides. Imides were prepared in good yields by carbonylation of a C(sp(3))-H bond of the cycloalkane with the amides acting as weak nucleophiles. Notably, this is the first report of copper-catalyzed carbonylative C-H activation.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available