4.7 Article

Endogenous Neurosteroid (3α,5α)3-Hydroxypregnan-20-one Inhibits Toll-like-4 Receptor Activation and Pro-inflammatory Signaling in Macrophages and Brain

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Characterisation of peptide interactions that regulate PKCε activation

Indu R. Chandrashekaran et al.

FEBS LETTERS (2018)

Review Biochemistry & Molecular Biology

The CRF Family of Neuropeptides and their Receptors - Mediators of the Central Stress Response

Nina Dedic et al.

CURRENT MOLECULAR PHARMACOLOGY (2018)

Editorial Material Neurosciences

The Neuroimmune Basis of Excessive Alcohol Consumption

Jody Mayfield et al.

NEUROPSYCHOPHARMACOLOGY (2017)

Review Neurosciences

Glial and Neuroimmune Mechanisms as Critical Modulators of Drug Use and Abuse

Michael J. Lacagnina et al.

NEUROPSYCHOPHARMACOLOGY (2017)

Article Biochemistry & Molecular Biology

C4b-binding protein negatively regulates TLR4/MD-2 response but not TLR3 response

Naoko Morita et al.

FEBS LETTERS (2017)

Review Biochemistry & Molecular Biology

The Role of Carbohydrates in the Lipopolysaccharide (LPS)/Toll-Like Receptor 4 (TLR4) Signalling

Florent Cochet et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Article Biochemical Research Methods

Characterization of the changes in eicosanoid profiles of activated macrophages treated with 20(S)-ginsenoside Rg3

Jae Won Lee et al.

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2017)

Article Medicine, General & Internal

Brexanolone (SAGE-547 injection) in post-partum depression: a randomised controlled trial

Stephen Kanes et al.

LANCET (2017)

Review Neurosciences

Neural regulation of immunity: molecular mechanisms and clinical translation

Valentin A. Pavlov et al.

NATURE NEUROSCIENCE (2017)

Review Neurosciences

The role of neuroimmune signaling in alcoholism

Fulton T. Crews et al.

NEUROPHARMACOLOGY (2017)

Review Neurosciences

Toll-like receptor signaling and stages of addiction

Fulton T. Crews et al.

PSYCHOPHARMACOLOGY (2017)

Article Substance Abuse

Alcohol and Stress Activation of Microglia and Neurons: Brain Regional Effects

Thomas Jordan Walter et al.

ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2017)

Article Behavioral Sciences

Impaired microglia fractalkine signaling affects stress reaction and coping style in mice

Zsuzsanna Winkler et al.

BEHAVIOURAL BRAIN RESEARCH (2017)

Article Substance Abuse

Ethanol, TLR3, and TLR4 Agonists Have Unique Innate Immune Responses in Neuron-Like SH-SY5Y and Microglia-Like BV2

Colleen J. Lawrimore et al.

ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2017)

Article Biochemistry & Molecular Biology

Dynamic lipopolysaccharide transfer cascade to TLR4/MD2 complex via LBP and CD14

Soo Jin Kim et al.

BMB REPORTS (2017)

Article Biochemistry & Molecular Biology

Ethanol-Induced TLR4/NLRP3 Neuroinflammatory Response in Microglial Cells Promotes Leukocyte Infiltration Across the BBB

Silvia Alfonso-Loeches et al.

NEUROCHEMICAL RESEARCH (2016)

Article Endocrinology & Metabolism

Effects of progesterone stimulated allopregnanolone on craving and stress response in cocaine dependent men and women

Verica Milivojevic et al.

PSYCHONEUROENDOCRINOLOGY (2016)

Review Neurosciences

Role of neuro-immunological factors in the pathophysiology of mood disorders

Anindya Bhattacharya et al.

PSYCHOPHARMACOLOGY (2016)

Article Behavioral Sciences

Early life stress is a risk factor for excessive alcohol drinking and impulsivity in adults and is mediated via a CRF/GABAA mechanism

Marjorie C. Gondre-Lewis et al.

STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS (2016)

Review Endocrinology & Metabolism

An Update on CRF Mechanisms Underlying Alcohol Use Disorders and Dependence

Isabel Marian Hartmann Quadros et al.

FRONTIERS IN ENDOCRINOLOGY (2016)

Article Neurosciences

CRF-Amplified Neuronal TLR4/MCP-1 Signaling Regulates Alcohol Self-Administration

Harry L. June et al.

NEUROPSYCHOPHARMACOLOGY (2015)

Review Biochemistry & Molecular Biology

Tyrosine phosphorylation in Toll-like receptor signaling

Saurabh Chattopadhyay et al.

CYTOKINE & GROWTH FACTOR REVIEWS (2014)

Article Immunology

Peripheral inflammation is associated with remote global gene expression changes in the brain

Carolyn A. Thomson et al.

JOURNAL OF NEUROINFLAMMATION (2014)

Review Neurosciences

Addiction as a stress surfeit disorder

George F. Koob et al.

NEUROPHARMACOLOGY (2014)

Article Multidisciplinary Sciences

Prolonged Neuroinflammation after Lipopolysaccharide Exposure in Aged Rats

Hui Qun Fu et al.

PLOS ONE (2014)

Review Neurosciences

Allopregnanolone and neuroinflammation: a focus on multiple sclerosis

Farshid Noorbakhsh et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2014)

Article Pharmacology & Pharmacy

Ethanol Activation of Protein Kinase A Regulates GABAA α1 Receptor Function and Trafficking in Cultured Cerebral Cortical Neurons

Stephen L. Carlson et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2013)

Article Pharmacology & Pharmacy

TLR4-MyD88 signalling: a molecular target for alcohol actions

Subhash C. Pandey

BRITISH JOURNAL OF PHARMACOLOGY (2012)

Review Immunology

HMGB1 Is a Therapeutic Target for Sterile Inflammation and Infection

Ulf Andersson et al.

ANNUAL REVIEW OF IMMUNOLOGY, VOL 29 (2011)

Review Immunology

Induction of innate immune genes in brain create the neurobiology of addiction

F. T. Crews et al.

BRAIN BEHAVIOR AND IMMUNITY (2011)

Article Multidisciplinary Sciences

Binge alcohol drinking is associated with GABAA α2-regulated Toll-like receptor 4 (TLR4) expression in the central amygdala

Juan Liu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Review Neurosciences

Toll-like receptor signaling in neural plasticity and disease

Eitan Okun et al.

TRENDS IN NEUROSCIENCES (2011)

Article Immunology

The Microtubule Regulator Stathmin Is an Endogenous Protein Agonist for TLR3

Malika Bsibsi et al.

JOURNAL OF IMMUNOLOGY (2010)

Article Neurosciences

Pivotal Role of TLR4 Receptors in Alcohol-Induced Neuroinflammation and Brain Damage

Silvia Alfonso-Loeches et al.

JOURNAL OF NEUROSCIENCE (2010)

Article Multidisciplinary Sciences

A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release

Huan Yang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Review Clinical Neurology

Toll-Like Receptor Tolerance as a Mechanism for Neuroprotection

Keri B. Vartanian et al.

TRANSLATIONAL STROKE RESEARCH (2010)

Review Biochemistry & Molecular Biology

LPS/TLR4 signal transduction pathway

Yong-Chen Lu et al.

CYTOKINE (2008)

Article Neurosciences

Increased MCP-1 and microglia in various regions of the human alcoholic brain

Jun He et al.

EXPERIMENTAL NEUROLOGY (2008)

Review Neurosciences

From inflammation to sickness and depression: when the immune system subjugates the brain

Robert Dantzer et al.

NATURE REVIEWS NEUROSCIENCE (2008)

Review Pharmacology & Pharmacy

Progesterone: Therapeutic opportunities for neuroprotection and myelin repair

Michael Schumacher et al.

PHARMACOLOGY & THERAPEUTICS (2007)

Article Emergency Medicine

ProTECT: A randomized clinical trial of progesterone for acute traumatic brain injury

David W. Wright et al.

ANNALS OF EMERGENCY MEDICINE (2007)

Article Neurosciences

SNPs on chips: The hidden genetic code in expression arrays

Elzbieta Sliwerska et al.

BIOLOGICAL PSYCHIATRY (2007)

Article Biochemistry & Molecular Biology

Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein

JS Park et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Neurosciences

The γ2 subunit of GABAA receptors is a substrate for palmitoylation by GODZ

CA Keller et al.

JOURNAL OF NEUROSCIENCE (2004)

Article Multidisciplinary Sciences

Neuroactive steroids reduce neuronal excitability by selectively enhancing tonic inhibition mediated by δ subunit-containing GABAA receptors

BM Stell et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Multidisciplinary Sciences

Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

P Scaffidi et al.

NATURE (2002)

Article Neurosciences

The role of GABAergic neuroactive steroids in ethanol action, tolerance and dependence

AL Morrow et al.

BRAIN RESEARCH REVIEWS (2001)