Related references
Note: Only part of the references are listed.The Oncojanus Paradigm of Respiratory Complex I
Giulia Leone et al.
GENES (2018)
Platinum-induced mitochondrial DNA mutations confer lower sensitivity to paclitaxel by impairing tubulin cytoskeletal organization
Giulia Girolimetti et al.
HUMAN MOLECULAR GENETICS (2017)
Macrophage migration inhibitory factor downregulation: a novel mechanism of resistance to anti-angiogenic therapy
B. A. Castro et al.
ONCOGENE (2017)
Tumor Microenvironment and Differential Responses to Therapy
Eishu Hirata et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2017)
Non-Canonical Mechanisms Regulating Hypoxia-Inducible Factor 1 Alpha in Cancer
Luisa Iommarini et al.
FRONTIERS IN ONCOLOGY (2017)
Microenvironmental regulation of tumour angiogenesis
Michele de Palma et al.
NATURE REVIEWS CANCER (2017)
Metformin as an adjuvant treatment for cancer: a systematic review and meta-analysis
C. Coyle et al.
ANNALS OF ONCOLOGY (2016)
Metformin for cancer prevention: a reason for optimism
Andrew T. Chan
LANCET ONCOLOGY (2016)
Metformin for chemoprevention of metachronous colorectal adenoma or polyps in post-polypectomy patients without diabetes: a multicentre double-blind, placebo-controlled, randomised phase 3 trial
Takuma Higurashi et al.
LANCET ONCOLOGY (2016)
The expanding role of metformin in cancer: an update on antitumor mechanisms and clinical development
Jun Gong et al.
TARGETED ONCOLOGY (2016)
A novel thiophene-3-carboxamide analog of annonaceous acetogenin exhibits antitumor activity via inhibition of mitochondrial complex I
Akinobu Akatsuka et al.
PHARMACOLOGY RESEARCH & PERSPECTIVES (2016)
Metformin Does Not Reduce Markers of Cell Proliferation in Esophageal Tissues of Patients With Barrett's Esophagus
Amitabh Chak et al.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2015)
Metformin in patients with advanced pancreatic cancer: a double-blind, randomised, placebo-controlled phase 2 trial
Sil Kordes et al.
LANCET ONCOLOGY (2015)
Neutrophils support lung colonization of metastasis-initiating breast cancer cells
Stefanie K. Wculek et al.
NATURE (2015)
Multiple strategies of oxygen supply in Drosophila malignancies identify tracheogenesis as a novel cancer hallmark
Daniela Grifoni et al.
SCIENTIFIC REPORTS (2015)
The Genomic Landscape of Renal Oncocytoma Identifies a Metabolic Barrier to Tumorigenesis
Shilpy Joshi et al.
CELL REPORTS (2015)
Mesenchymal Cancer Cell-Stroma Crosstalk Promotes Niche Activation, Epithelial Reversion, and Metastatic Colonization
Yaiza del Pozo Martin et al.
CELL REPORTS (2015)
Metformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent Biosynthesis
Takla Griss et al.
PLOS BIOLOGY (2015)
Targeting mitochondrial complex I using BAY 87-2243 reduces melanoma tumor growth
Laura Schoeckel et al.
CANCER & METABOLISM (2015)
Anti-inflammatory M2, but not pro-inflammatory M1 macrophages promote angiogenesis in vivo
Nadine Jetten et al.
ANGIOGENESIS (2014)
Different mtDNA mutations modify tumor progression in dependence of the degree of respiratory complex I impairment
Luisa Iommarini et al.
HUMAN MOLECULAR GENETICS (2014)
Cancer-associated fibroblasts and M2-polarized macrophages synergize during prostate carcinoma progression
G. Comito et al.
ONCOGENE (2014)
The Monocyte to Macrophage Transition in the Murine Sterile Wound
Meredith J. Crane et al.
PLOS ONE (2014)
Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer
Young Seok Ju et al.
ELIFE (2014)
Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis
William W. Wheaton et al.
ELIFE (2014)
Metformin Decreases Glucose Oxidation and Increases the Dependency of Prostate Cancer Cells on Reductive Glutamine Metabolism
Sarah-Maria Fendt et al.
CANCER RESEARCH (2013)
Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis
Jessie Yanxiang Guo et al.
GENES & DEVELOPMENT (2013)
Complex I impairment in mitochondrial diseases and cancer: Parallel roads leading to different outcomes
Luisa Iommarini et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2013)
Epithelial neoplasia in Drosophila entails switch to primitive cell states
Sumbul J. Khan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Relevance of Mitochondrial Genetics and Metabolism in Cancer Development
Giuseppe Gasparre et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)
Respiratory complex I is essential to induce a Warburg profile in mitochondria-defective tumor cells
Claudia Calabrese et al.
CANCER & METABOLISM (2013)
Somatic mitochondrial DNA mutations in cancer escape purifying selection and high pathogenicity mutations lead to the oncocytic phenotype: pathogenicity analysis of reported somatic mtDNA mutations in tumors
Luisa Pereira et al.
BMC CANCER (2012)
Mitochondrial DNA Mutation in Serous Ovarian Cancer: Implications for Mitochondria-Coded Genes in Chemoresistance
Flora Guerra et al.
JOURNAL OF CLINICAL ONCOLOGY (2012)
Dual Effect of Metformin on Breast Cancer Proliferation in a Randomized Presurgical Trial
Bernardo Bonanni et al.
JOURNAL OF CLINICAL ONCOLOGY (2012)
Reductive carboxylation supports growth in tumour cells with defective mitochondria
Andrew R. Mullen et al.
NATURE (2012)
HRG Inhibits Tumor Growth and Metastasis by Inducing Macrophage Polarization and Vessel Normalization through Downregulation of PIGF
Charlotte Rolny et al.
CANCER CELL (2011)
A Mutation Threshold Distinguishes the Antitumorigenic Effects of the Mitochondrial Gene MTND1, an Oncojanus Function
Giuseppe Gasparre et al.
CANCER RESEARCH (2011)
PI3K and ERK-Induced Rac1 Activation Mediates Hypoxia-Induced HIF-1α Expression in MCF-7 Breast Cancer Cells
Jun Du et al.
PLOS ONE (2011)
Otto Warburg's contributions to current concepts of cancer metabolism
Willem H. Koppenol et al.
NATURE REVIEWS CANCER (2011)
The genetic and metabolic signature of oncocytic transformation implicates HIF1α destabilization
Anna Maria Porcelli et al.
HUMAN MOLECULAR GENETICS (2010)
The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments
Stephen A. Bustin et al.
CLINICAL CHEMISTRY (2009)
Reactivating HIF prolyl hydroxylases under hypoxia results in metabolic catastrophe and cell death
D. A. Tennant et al.
ONCOGENE (2009)
Activation of C-transactivation domain is essential for optimal HIF-1α-mediated transcriptional and angiogenic effects
Reshef Tal et al.
MICROVASCULAR RESEARCH (2008)
Oxygen sensing by metazoans: The central role of the HIF hydroxylase pathway
William G. Kaelin et al.
MOLECULAR CELL (2008)
Cell-permeating α-ketoglutarate derivatives alleviate pseudohypoxia in succinate dehydrogenase-deficient cells
Elaine D. MacKenzie et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Differences in reactive oxygen species production explain the phenotypes associated with common mouse mitochondrial DNA variants
Raquel Moreno-Loshuertos et al.
NATURE GENETICS (2006)
Contribution of somatic mutations in the mitochondrial genome to the development of cancer and tolerance against anticancer drugs
S. Ohta
ONCOGENE (2006)
Statistical analysis of real-time PCR data
JS Yuan et al.
BMC BIOINFORMATICS (2006)
The human protein Hugl-1 substitutes for Drosophila Lethal giant larvae tumour suppressor function in vivo
D Grifoni et al.
ONCOGENE (2004)
Inhibition of endogenous HIF inactivation induces angiogenesis in ischaemic skeletal muscles of mice
M Milkiewicz et al.
JOURNAL OF PHYSIOLOGY-LONDON (2004)
Redistribution of intracellular oxygen in hypoxia by nitric oxide:: Effect on HIF1α
T Hagen et al.
SCIENCE (2003)
Mfold web server for nucleic acid folding and hybridization prediction
M Zuker
NUCLEIC ACIDS RESEARCH (2003)
Share Paper
