Journal
TETRAHEDRON
Volume 75, Issue 11, Pages 1481-1491Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2019.01.066
Keywords
I-2, direct synthesis; Imidazo[1,2-a]pyridine; Benzo[d]imidazo[2,1-b]thiazole; 3-Phenoxy imidazo heterocycles
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Funding
- National Natural Science Foundation of China [21105091, 21172201]
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An I-2-mediated protocol was proposed for the synthesis of 3-phenoxy imidazo heterocycles from aromatic ketones and 2-aminopyridines or 2-aminobenzothiazole. This direct, efficient and operationally simple method provided a fundamentally novel and rapid approach for the synthesis of 3-phenoxy imidazo heterocycles with good to excellent yields, and it avoided the requirement of any metal, base and extra oxidant. (C) 2019 Elsevier Ltd. All rights reserved.
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