Journal
TETRAHEDRON
Volume 75, Issue 10, Pages 1311-1314Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2019.01.065
Keywords
E-factor; Green chemistry; Peroxygenases; Oxyfunctionalisation chemistry; Biocatalysis
Categories
Funding
- European Union [H2020-BBI-PPP-2015-2-720297-ENZOX2]
- European Research Council (ERC Consolidator Grant) [648026]
- Netherlands Organisation for Scientific Research through a VICI grant [724.014.003]
- United States National Science Foundation [IIP-1540017]
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The E-factor has become an important measure for the environmental impact of (bio)chemical reactions, However, summing up the obvious wastes generated in the laboratory neglects energy-related wastes (mostly greenhouse gases) which are generated elsewhere. To estimate these wastes, we propose to extend the E-factor by an energy-term (E+-factor). At the example of a lab-scale enzyme fermentation, we demonstrate that the E+-factor can constitute a multiple of the classical E-factor and therefore must not be neglected striving for a holistic estimation of the environmental impact. (C) 2019 The Authors. Published by Elsevier Ltd.
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