Journal
SURGERY FOR OBESITY AND RELATED DISEASES
Volume 15, Issue 5, Pages 739-748Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.soard.2019.01.008
Keywords
Bariatric surgery; Gastric bypass; Laparoscopic adjustable gastric banding; Mental disorders; Weight change; Quality of life; Mood disorders
Categories
Funding
- National Institute of Diabetes and Digestive and Kidney Diseases [DSS-U01DK066557, R01 DK084979]
- National Institute of Diabetes and Digestive and Kidney Diseases (Columbia [Cornell University Medical Center CTSC]) [U01-DK66667, UL1-RR024996]
- National Institute of Diabetes and Digestive and Kidney Diseases (Neuropsychiatric Research Institute) [U01-DK66471]
- National Institute of Diabetes and Digestive and Kidney Diseases (University of Pittsburgh Medical Center [CTRC]) [U01-DK66585, UL1-RR0241531]
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Background: Long-term, longitudinal data are limited on mental disorders after bariatric surgery. Objective: To report mental disorders through 7 years postsurgery and examine their relationship with changes in weight and health-related quality of life. Setting: Three U.S. academic medical centers. Method: As a substudy of the Longitudinal Assessment of Bariatric Surgery Consortium, 199 adults completed the structured clinical interview for Diagnostic and Statistical Manual of Mental Disorders, 4th Edition prior to Roux-en-Y gastric bypass (RYGB) or laparoscopic adjustable gastric band. Participants who completed >= 1 follow-up through 7 years postsurgery are included (n = 173; 86.9%). Mixed models were used to examine mental disorders over time, and among the RYGB subgroup (n=104), their relationship with long-term (>= 4 yr) pre- to postsurgery changes in weight and health-related quality of life, measured with the Short Form-36 Health Survey, and with weight regain from nadir. Results: Compared with presurgery (34.7%), the prevalence of having any mental disorder was significantly lower 4 years (21.3%; P < .01) and 5 years (19.2%; P = .01), but not 7 years (29.1%; P = .27) after RYGB. The most common disorders were not related to long-term weight loss postRYGB. However, independent of weight change, mood and anxiety disorders, both pre-and postRYGB, were significantly related to less improvement in mental (but not physical) health-related quality of life. Having a concurrent mood disorder appeared to be associated with greater weight regain (6.4% of maximum weight lost, 95% confidence interval, -.3 to 13.1), but this was not statistically significant (P = .06). Conclusions: Bariatric surgery does not result in consistent long-term reductions in mental disorders. Mood disorders may impact long-term outcomes of bariatric surgery. (C) 2019 Published by Elsevier Inc. on behalf of American Society for Bariatric Surgery.
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