Journal
SENSORS
Volume 19, Issue 3, Pages -Publisher
MDPI
DOI: 10.3390/s19030554
Keywords
paper-based immunoassays; lateral flow assay; biological sensors; dipstick assay; rapid diagnostics
Funding
- Rafael del Pino Fellowship
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Paper-based sensors and assays have been highly attractive for numerous biological applications, including rapid diagnostics and assays for disease detection, food safety, and clinical care. In particular, the paper immunoassay has helped drive many applications in global health due to its low cost and simplicity of operation. This review is aimed at examining the fundamentals of the technology, as well as different implementations of paper-based assays and discuss novel strategies for improving their sensitivity, performance, or enabling new capabilities. These innovations can be categorized into using unique nanoparticle materials and structures for detection via different techniques, novel biological species for recognizing biomarkers, or innovative device design and/or architecture.
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