Journal
SCIENCE
Volume 363, Issue 6430, Pages 947-+Publisher
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.aau0780
Keywords
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Funding
- Bill & Melinda Gates Foundation [PP1182909, OPP1193311]
- Gerber Foundation
- Friends of Prentice Foundation
- RIE2020 AME Programmatic Grant - A*STAR-SERC, Singapore [A18A1b0045]
- National Natural Science Foundation of China [11402134, 11320101001]
- National Basic Research Program of China [2015CB351900]
- NSF [1534120, 1635443]
- Future Growth Engine Program - Ministry of Trade, Industry & Energy (MOTIE, South Korea) [10079974]
- Systems on Nanoscale Information Fabrics (SONIC) - Microelectronics Advanced Research Corporation (MARCO)
- Defense Advanced Research Projects Agency (DARPA)
- Soft and Hybrid Nanotechnology Experimental (SHyNE) Resource [NSF ECCS-1542205]
- Materials Research Science and Engineering Center [DMR-1720139]
- State of Illinois
- Northwestern University
- Bill and Melinda Gates Foundation [OPP1193311] Funding Source: Bill and Melinda Gates Foundation
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Existing vital signmonitoring systems in the neonatal intensive care unit (NICU) requiremultiple wires connected to rigid sensors with strongly adherent interfaces to the skin. We introduce a pair of ultrathin, soft, skin-like electronic devices whose coordinated, wireless operation reproduces the functionality of these traditional technologies but bypasses their intrinsic limitations. The enabling advances in engineering science include designs that support wireless, battery-free operation; real-time, in-sensor data analytics; time-synchronized, continuous data streaming; soft mechanics and gentle adhesive interfaces to the skin; and compatibility with visual inspection and with medical imaging techniques used in the NICU. Preliminary studies on neonates admitted to operating NICUs demonstrate performance comparable to the most advanced clinical-standard monitoring systems.
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