Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 116, Issue 12, Pages 5633-5642Publisher
NATL ACAD SCIENCES
DOI: 10.1073/pnas.1820320116
Keywords
Podarcis muralis; carotenoid pigmentation; pterin pigmentation; balanced polymorphism; introgression
Categories
Funding
- Knut and Alice Wallenberg Foundations
- Swedish Research Council [2017-02907, E0446501]
- Fundacao para a Ciencia e Tecnologia (FCT) through POPH-QREN funds from the European Social Fund
- Fundacao para a Ciencia e Tecnologia (FCT) through Portuguese MCTES (FCT Investigator Grants) [IF/00283/2014/CP1256/CT0012, IF/01597/2014/CP1256/CT0009, SFRH/BPD/99138/2013, SFRH/BPD/94582/2013]
- Wallenberg Academy Fellowship
- NORTE2020 through Portugal 2020 [PTDC/BIA-EVL/30288/2017 -NORTE -01-0145-FEDER-30288]
- NORTE2020 through FEDER Funds [PTDC/BIA-EVL/30288/2017 -NORTE -01-0145-FEDER-30288]
- FCT
- project Genomics and Evolutionary Biology - North Portugal Regional Operational Programme 2007/2013 (ON. 2 -O Novo Norte) under the National Strategic Reference Framework
- project Genomics Applied to Genetic Resources - North Portugal Regional Operational Programme 2007/2013 (ON. 2 -O Novo Norte) under the National Strategic Reference Framework
- European Regional Development Fund
- European Union FP7 REGPOT grant (CIBIO-New-Gen) [286431]
- program Rita Levi Montalcini (Ministero dell'Istruzione dell'Universita e della Ricerca)
- RFI/VR
- Science for Life Laboratory, Sweden
- [PD/BD/114028/2015]
- [PD/BD/128492/2017]
- [NORTE-01-0145-FEDER-000007]
- Fundação para a Ciência e a Tecnologia [SFRH/BPD/94582/2013, IF/00283/2014/CP1256/CT0012, IF/01597/2014/CP1256/CT0009] Funding Source: FCT
- Swedish Research Council [2017-02907] Funding Source: Swedish Research Council
Ask authors/readers for more resources
Reptiles use pterin and carotenoid pigments to produce yellow, orange, and red colors. These conspicuous colors serve a diversity of signaling functions, but their molecular basis remains unresolved. Here, we show that the genomes of sympatric color morphs of the European common wall lizard (Podarcis muralis), which differ in orange and yellow pigmentation and in their ecology and behavior, are virtually undifferentiated. Genetic differences are restricted to two small regulatory regions near genes associated with pterin [sepiapterin reductase (SPR)] and carotenoid [beta-carotene oxygenase 2 (BCO2)] metabolism, demonstrating that a core gene in the housekeeping pathway of pterin biosynthesis has been coopted for bright coloration in reptiles and indicating that these loci exert pleiotropic effects on other aspects of physiology. Pigmentation differences are explained by extremely divergent alleles, and haplotype analysis revealed abundant transspecific allele sharing with other lacertids exhibiting color polymorphisms. The evolution of these conspicuous color ornaments is the result of ancient genetic variation and cross-species hybridization.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available