Journal
PHYTOCHEMISTRY
Volume 158, Issue -, Pages 13-19Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.phytochem.2018.10.035
Keywords
Fusarium solani; Fusaric acid derivatives; gamma-pyrone derivatives; Antibacterial activity
Categories
Funding
- NSFC-Shandong Joint Fund for Marine Science Research Centers [U1606403]
- Fundamental Research Funds for the Central Universities [201822019, 201562016]
- Qingdao National Laboratory for Marine Science and Technology [2015ASKJ02, 2016ASKJ08-02]
- City of Qingdao [2017-CXZX01-3-6]
Ask authors/readers for more resources
Seven compounds including four undescribed fusaric acid derivatives, namely fusaricates H-K, and two undescribed gamma-pyrone derivatives, named fusolanones A-B, as well as a known compound fusaric acid, were isolated from a mangrove endophytic fungus Fusarium solani. Fusaricates H-K represent the first cases of fusaric acid butanediol esters and are diastereoisomers. Their structures including absolute configurations were elucidated based on NMR, MS, chemical synthesis, chiral HPLC analysis and ECD calculations. The antibacterial activity of all undescribed compounds were tested and fusolanone B showed the best activity with MIC value 6.25 mu g/mL on Vibrio parahaemolyticus.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available