Journal
ORGANIC LETTERS
Volume 21, Issue 6, Pages 1668-1671Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.9b00214
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Funding
- Project of Ministry of Education of China Double Top-Class [yldxxk2018]
- Promotion Program for Young Teacher in Science and Technology Research of Minzu University of China [317201961]
- National Science Foundation of China [91744206]
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In this letter, we successfully explored a cascade Pd/Cu-catalyzed intermolecular C(sp(3))-H arylation of amides and intramolecular C-N coupling reaction. This method provides a one-pot strategy to synthesize 3,4-2H-quinolinone with good regioselectivity of C-H arylation and C-N coupling from C-I and C-X bonds from readily available starting materials.
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