Journal
ORGANIC LETTERS
Volume 21, Issue 4, Pages 1161-1164Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.9b00104
Keywords
-
Categories
Funding
- NSFC [21272002, 21472150, 21871223]
- Chongqing Science Technology Commission [cstccxljrc201701, cstc2018jcyjAX0548]
Ask authors/readers for more resources
The first catalytic asymmetric Diels-Alder reaction of 3-vinylindole and nitroolefin is described. In the promotion of organocatalyst 3j, structurally diverse 1-nitro-hydrocarbazoles are produced in moderate-to-good yields and high-to-excellent enantioselectivities. All of these products are obtained as a single diastereoisomer. The 1-nitro-hydrocarbazole compounds can be converted into 1-amino-hydrocarbazole derivatives and structurally complex ring fused indoles enantioseletively. Possible transition states were investigated by control experiments and DFT calculations.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available