Related references
Note: Only part of the references are listed.KPNA2 promotes migration and invasion in epithelial ovarian cancer cells by inducing epithelial-mesenchymal transition via Akt/GSK-3β/Snail activation
Long Huang et al.
JOURNAL OF CANCER (2018)
A Small Organic Molecule Blocks EGFR Transport into the Nucleus by the Nonclassical Pathway Resulting in Repression of Cancer Invasion
Siyoung Ha et al.
CHEMBIOCHEM (2018)
Inhibition of KPNA4 attenuates prostate cancer metastasis
J. Yang et al.
ONCOGENE (2017)
In vivo loss-of-function screens identify KPNB1 as a new druggable oncogene in epithelial ovarian cancer
Michiko Kodama et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Importin β1 targeting by hepatitis C virus NS3/4A protein restricts IRF3 and NF-κB signaling of IFNB1 antiviral response
Bridget Gagne et al.
TRAFFIC (2017)
Search for KPNA7 cargo proteins in human cells reveals MVP and ZNF414 as novel regulators of cancer cell growth
Elisa M. Vuorinen et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2017)
Karyopherin Alpha 2 Promotes the Inflammatory Response in Rat Pancreatic Acinar Cells Via Facilitating NF-κB Activation
Yongxia Cai et al.
DIGESTIVE DISEASES AND SCIENCES (2016)
Karyopherinb1 regulates proliferation of human glioma cells via Wnt/β-catenin pathway
Ting Lu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)
Targeting nuclear transporters in cancer: Diagnostic, prognostic and therapeutic potential
Tamara Stelma et al.
IUBMB LIFE (2016)
Targeting the Nuclear Import Receptor Kpnβ1 as an Anticancer Therapeutic
Pauline J. van der Watt et al.
MOLECULAR CANCER THERAPEUTICS (2016)
Latcripin-13 domain induces apoptosis and cell cycle arrest at the G1 phase in human lung carcinoma A549 cells
Jia Wang et al.
ONCOLOGY REPORTS (2016)
Importins and exportins as therapeutic targets in cancer
Amit Mahipal et al.
PHARMACOLOGY & THERAPEUTICS (2016)
Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer
Amira Elgogary et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Myc and cell cycle control
Gabriel Bretones et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2015)
Hyper-dependence of breast cancer cell types on the nuclear transporter Importin β1
Henna V. Kuusisto et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2015)
KPNA2 is a nuclear export protein that contributes to aberrant localisation of key proteins and poor prognosis of breast cancer
A. T. Alshareeda et al.
BRITISH JOURNAL OF CANCER (2015)
Importin β1 mediates nuclear factor-κB signal transduction into the nuclei of myeloma cells and affects their proliferation and apoptosis
Wenqing Yan et al.
CELLULAR SIGNALLING (2015)
KPNβ1 promotes palmitate-induced insulin resistance via NF-κB signaling in hepatocytes
Suxin Wang et al.
JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY (2015)
Suppression of the nuclear transporter-KPN beta 1 expression inhibits tumor proliferation in hepatocellular carcinoma
Linlin Yang et al.
MEDICAL ONCOLOGY (2015)
Antitumor effects of pharmacological EZH2 inhibition on malignant peripheral nerve sheath tumor through the miR-30a and KPNB1 pathway
Pingyu Zhang et al.
MOLECULAR CANCER (2015)
Upregulation of miR-181s reverses mesenchymal transition by targeting KPNA4 in glioblastoma
Hongjun Wang et al.
SCIENTIFIC REPORTS (2015)
Inhibition of the nuclear transporter, Kpnβ1, results in prolonged mitotic arrest and activation of the intrinsic apoptotic pathway in cervical cancer cells
Liselotte Angus et al.
CARCINOGENESIS (2014)
KPNA7, a nuclear transport receptor, promotes malignant properties of pancreatic cancer cells in vitro
Eeva Laurila et al.
EXPERIMENTAL CELL RESEARCH (2014)
Prosurvival Function of the Cellular Apoptosis Susceptibility/Importin-α1 Transport Cycle Is Repressed by p53 in Liver Cancer
Juliane Winkler et al.
HEPATOLOGY (2014)
EZH2-miR-30d-KPNB1 pathway regulates malignant peripheral nerve sheath tumour cell survival and tumourigenesis
Pingyu Zhang et al.
JOURNAL OF PATHOLOGY (2014)
Nuclear import and export inhibitors alter capsid protein distribution in mammalian cells and reduce Venezuelan Equine Encephalitis Virus replication
Lindsay Lundberg et al.
ANTIVIRAL RESEARCH (2013)
Nuclear karyopherin-2 expression in primary lesions and metastatic lymph nodes was associated with poor prognosis and progression in gastric cancer
Bolag Altan et al.
CARCINOGENESIS (2013)
Metformin targets c-MYC oncogene to prevent prostate cancer
Tunde Akinyeke et al.
CARCINOGENESIS (2013)
Functional Genetic Screens Identify Genes Essential for Tumor Cell Survival in Head and Neck and Lung Cancer
Sanne R. Martens-de Kemp et al.
CLINICAL CANCER RESEARCH (2013)
KPNA2 promotes cell proliferation and tumorigenicity in epithelial ovarian carcinoma through upregulation of c-Myc and downregulation of FOXO3a
L. Huang et al.
CELL DEATH & DISEASE (2013)
Importazole, a Small Molecule Inhibitor of the Transport Receptor Importin-β
Jonathan F. Soderholm et al.
ACS CHEMICAL BIOLOGY (2011)
Overexpression of Kpnβ1 and Kpnα2 Importin Proteins in Cancer Derives from Deregulated E2F Activity
Pauline J. van der Watt et al.
PLOS ONE (2011)
Live-cell imaging RNAi screen identifies PP2A-B55α and importin-β1 as key mitotic exit regulators in human cells
Michael H. A. Schmitz et al.
NATURE CELL BIOLOGY (2010)
The RCC1 superfamily: From genes, to function, to disease
Ouadah Hadjebi et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2008)
Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesis
Bora Gurel et al.
MODERN PATHOLOGY (2008)
RCC1 isoforms differ in their affinity for chromatin, molecular interactions and regulation by phosphorylation
Fiona E. Hood et al.
JOURNAL OF CELL SCIENCE (2007)
N-terminal α-methylation of RCC1 is necessary for stable chromatin association and normal mitosis
Ting Chen et al.
NATURE CELL BIOLOGY (2007)
Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach
Heike B. Koch et al.
CELL CYCLE (2007)
Nuclear-cytoplasmic transport of EGFR involves receptor endocytosis, importin β1 and CRM1
Hui-Wen Lo et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2006)
Context-dependent hormone-refractory progression revealed through characterization of a novel murine prostate cancer cell line
PA Watson et al.
CANCER RESEARCH (2005)
Nuclear import of the respiratory syncytial virus matrix protein is mediated by importin β1 independent of importin α
R Ghildyal et al.
BIOCHEMISTRY (2005)
NF-κB is transported into the nucleus by importin α3 and importin α4
R Fagerlund et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Nuclear factor-κB inhibitors as sensitizers to anticancer drugs
C Nakanishi et al.
NATURE REVIEWS CANCER (2005)
Phosphorylation regulates the dynamic interaction of RCC1 with chromosomes during mitosis
JRA Hutchins et al.
CURRENT BIOLOGY (2004)
Myc-driven murine prostate cancer shares molecular features with human prostate tumors
K Ellwood-Yen et al.
CANCER CELL (2003)
Targeting of RCC1 to chromosomes is required for proper mitotic spindle assembly in human cells
WJ Moore et al.
CURRENT BIOLOGY (2002)
NF-κB in cancer:: From innocent bystander to major culprit
M Karin et al.
NATURE REVIEWS CANCER (2002)