Journal
NEURON
Volume 101, Issue 5, Pages 783-800Publisher
CELL PRESS
DOI: 10.1016/j.neuron.2019.02.019
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Funding
- Wellcome Trust
- Nuffield Benefaction
- NIH [NS105076]
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Pain is a subjective sensory experience that can, mostly, be reported but cannot be directly measured or quantified. Nevertheless, a suite of biomarkers related to mechanisms, neural activity, and susceptibility offer the possibility-especially when used in combination-to produce objective pain-related indicators with the specificity and sensitivity required for diagnosis and for evaluation of risk of developing pain and of analgesic efficacy. Such composite biomarkers will also provide improved understanding of pain pathophysiology.
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