Journal
NATURE NEUROSCIENCE
Volume 22, Issue 3, Pages 333-334Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/s41593-019-0343-1
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Excessive synapse elimination during adolescence and early adulthood has long been hypothesized to underpin the emergence of schizophrenia. A new study reports that induced microglia-like cells derived from schizophrenia patients display increased synapse engulfment, which may be partly mediated by a genetic schizophrenia-risk variant.
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