Journal
NATURAL PRODUCT RESEARCH
Volume 34, Issue 9, Pages 1297-1302Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2018.1556652
Keywords
Ligularia dictyoneura; compositae; eremophilane
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Funding
- Key Laboratory in Yunnan, China [2016-5]
- Science and Technology Innovation Team of Higher Education in Yunnan, China [2014-6]
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Two new eremophilane sesquiterpenoides, 6 alpha,9 alpha-dihydroxyeremophilenolide (1), and 1 beta,10 beta-dihydroxyeremophilenolide (2), along with ten known eremophilane sesquiterpenoides (3-12) were isolated from the aerial parts of Ligularia dictyoneura (Franch.) Hand.-Mazz. Their structures were elucidated by means of extensive spectroscopic analysis. Compounds 3-6 were assessed for their cytotoxicity against five human cancer cell lines (HL-60, SMMC-7721, A-549, MCF-7 and SW-480), and the result showed that they had no activity.
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