Trichosordarin A, a norditerpene glycoside from the marine-derived fungusTrichoderma harzianumR5

A new sordarin derivative, trichosordarin A (1), with a unique norditerpene aglycone was isolated from the culture of a marine-sediment-derived fungal strain,Trichoderma harzianumR5. Its structure and relative configuration were unequivocally identified by a combination of 1D/2D NMR, IR, and mass spectrometric methods. Compound1was assayed to be toxic to the marine zooplanktonArtemia salina.