4.2 Article

A convenient synthesis of spiroindolo[2,1-b]quinazoline-6,2′-[1,3,4]oxadiazoles from tryptanthrin and nitrile imines

Journal

MONATSHEFTE FUR CHEMIE
Volume 150, Issue 6, Pages 1093-1099

Publisher

SPRINGER WIEN
DOI: 10.1007/s00706-019-2367-3

Keywords

Spiro compound; 1,3-Dipolar cycloaddition; Tryptanthrin; 1,3,4-Oxadiazole; Azomethine ylide

Funding

  1. Research Council of Tarbiat Modares University

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A convenient method for the synthesis of functionalized spiroindolo[2,1-b]quinazoline-6,2-[1,3,4]oxadiazoles from indolo[2,1-b]quinazoline-6,12-diones and 13 hydrazonoyl chlorides in refluxing MeCN is described. These transformations are highlighted by inert atmosphere and lack of activator or metal promoters.

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