Related references
Note: Only part of the references are listed.Computational screening of chalcones acting against topoisomerase II alpha and their cytotoxicity towards cancer cell lines
Kanyani Sangpheak et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2019)
Computational screening of fatty acid synthase inhibitors against thioesterase domain
Wanwisa Panman et al.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2018)
Design, Synthesis and Cytotoxic Evaluation of Novel Chalcone Derivatives Bearing Triazolo[4,3-a]-quinoxaline Moieties as Potent Anticancer Agents with Dual EGFR Kinase and Tubulin Polymerization Inhibitory Effects
Mohamed Alswah et al.
MOLECULES (2018)
EGFR-targeting, β-defensin-tailored fusion protein exhibits high therapeutic efficacy against EGFR-expressed human carcinoma via mitochondria-mediated apoptosis
Wen-Juan Liu et al.
ACTA PHARMACOLOGICA SINICA (2018)
Cytotoxicity, molecular modeling, cell cycle arrest, and apoptotic induction induced by novel tetrahydro-[1,2,4]triazolo[3,4-a]isoquinoline chalcones
Magda F. Mohamed et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)
Epidermal growth factor receptor peptide vaccination induces cross-reactive immunity to human EGFR, HER2, and HER3
Hester A. Doyle et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2018)
Molecular recognition of naphthoquinone-containing compounds against human DNA topoisomerase IIα ATPase domain: A molecular modeling study
Panupong Mahalapbutr et al.
JOURNAL OF MOLECULAR LIQUIDS (2017)
Shikonin inhibits gefitinib-resistant non-small cell lung cancer by inhibiting TrxR and activating the EGFR proteasomal degradation pathway
Xia Li et al.
PHARMACOLOGICAL RESEARCH (2017)
Non-small cell lung cancer (NSCLC), EGFR downstream pathway activation and TKI targeted therapies sensitivity: Effect of the plasma membrane-associated NEU3
Matilde Forcella et al.
PLOS ONE (2017)
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
Antoine Daina et al.
SCIENTIFIC REPORTS (2017)
Rational design of non-resistant targeted cancer therapies
Francisco Martinez-Jimenez et al.
SCIENTIFIC REPORTS (2017)
PD-L1 overexpression is partially regulated by EGFR/HER2 signaling and associated with poor prognosis in patients with non-small-cell lung cancer
Riki Okita et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2017)
Synthesis and topoisomerases inhibitory activity of heteroaromatic chalcones
Kyung-Hwa Jeon et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2016)
Synthesis, spectral characterization and in vitro antibacterial evaluation and Petra/Osiris/Molinspiration analyses of new Palladium(II) iodide complexes with thioamides
Shafqat Nadeem et al.
ALEXANDRIA JOURNAL OF MEDICINE (2016)
Structure guided design and binding analysis EGFR inhibiting analogues of erlotinib and AEE788 using ensemble docking, molecular dynamics and MM-GBSA
Vishnu K. Sharma et al.
RSC ADVANCES (2016)
Quantification of Epidermal Growth Factor Receptor Expression Level and Binding Kinetics on Cell Surfaces by Surface Plasmon Resonance Imaging
Fenni Zhang et al.
ANALYTICAL CHEMISTRY (2015)
Inhibition of class IA PI3K enzymes in non-small cell lung cancer cells uncovers functional compensation among isoforms
Christopher Stamatkin et al.
CANCER BIOLOGY & THERAPY (2015)
Anti-cancer chalcones: Structural and molecular target perspectives
Debarshi Mar Mahapatra et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2015)
Data Warrior: An Open-Source Program For Chemistry Aware Data Visualization And Analysis
Thomas Sander et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2015)
ff14SB: Improving the Accuracy of Protein Side Chain and Backbone Parameters from ff99SB
James A. Maier et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2015)
Afatinib resistance in non-small cell lung cancer involves the PI3K/AKT and MAPK/ERK signalling pathways and epithelial-to-mesenchymal transition
Simona Coco et al.
TARGETED ONCOLOGY (2015)
Molecular docking based screening of novel designed chalcone series of compounds for their anti-cancer activity targeting EGFR kinase domain
Chennu Maruthi Malya Prasada Rao et al.
BIOINFORMATION (2015)
Synthesis of novel β-carboline based chalcones with high cytotoxic activity against breast cancer cells
Shikha S. Chauhan et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2014)
Novel anthraquinone based chalcone analogues containing an imine fragment: Synthesis, cytotoxicity and anti-angiogenic activity
Branka Kolundzija et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2014)
Synthesis and evaluation of novel isoxazolyl chalcones as potential anticancer agents
Maosheng Wan et al.
BIOORGANIC CHEMISTRY (2014)
Molecular Targeted Approaches to Cancer Therapy and Prevention Using Chalcones
Danielle D. Jandial et al.
CURRENT CANCER DRUG TARGETS (2014)
Recent developments in biological activities of chalcones: A mini review
Parvesh Singh et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2014)
Design and Development of Halogenated Chalcone Derivatives as Potential Anticancer Agents
Upendra K. Jain et al.
TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH (2014)
Chalcones, inhibitors for topoisomerase I and cathepsin B and L, as potential anti-cancer agents
Seok-Ho Kim et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)
Cytotoxic and apoptotic effects of chalcone derivatives of 2-acetyl thiophene on human colon adenocarcinoma cells
Alana de Vasconcelos et al.
CELL BIOCHEMISTRY AND FUNCTION (2013)
In silico design: Extended molecular dynamic simulations of a new series of dually acting inhibitors against EGFR and HER2
Marawan Ahmed et al.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING (2013)
Synthesis and Characterization of Ru(II)-DMSO-Cl-Chalcone Complexes: DNA Binding, Nuclease, and Topoisomerase II Inhibitory Activity
Ruchi Gaur et al.
INORGANIC CHEMISTRY (2012)
Thermal solvent-free synthesis of chromonyl chalcones, pyrazolines and their in vitro antibacterial, antifungal activities
Zeba N. Siddiqui et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2012)
Targeting KRAS-Mutant Non-Small Cell Lung Cancer with the Hsp90 Inhibitor Ganetespib
Jaime Acquaviva et al.
MOLECULAR CANCER THERAPEUTICS (2012)
Dacomitinib (PF-00299804), an Irreversible Pan-HER Inhibitor, Inhibits Proliferation of HER2-Amplified Breast Cancer Cell Lines Resistant to Trastuzumab and Lapatinib
Ondrej Kalous et al.
MOLECULAR CANCER THERAPEUTICS (2012)
Synthesis of Chalcones with Anticancer Activities
Suvitha Syam et al.
MOLECULES (2012)
PROPKA3: Consistent Treatment of Internal and Surface Residues in Empirical pKa Predictions
Mats H. M. Olsson et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2011)
Synthesis and biological evaluation of retinoid-chalcones as inhibitors of colon cancer cell growth
Cassia S. Mizuno et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
The synthesis and Angiotensin Converting Enzyme (ACE) inhibitory activity of chalcones and their pyrazole derivatives
Marco Bonesi et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
Gefitinib or Chemotherapy for Non-Small-Cell Lung Cancer with Mutated EGFR.
Makoto Maemondo et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Synthesis, physicochemical properties and antimicrobial evaluation of new (E)-chalcones
Z. Nowakowska et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2008)
In-vitro evaluation of selected chalcones for antioxidant activity
R. N. Gacche et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2008)
BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models
D. Li et al.
ONCOGENE (2008)
Improved and rapid synthesis of new coumarinyl chalcone derivatives and their antiviral activity
Jalpa C. Trivedi et al.
TETRAHEDRON LETTERS (2007)
Characterization of a novel tripartite nuclear localization sequence in the EGFR family
Sheng-Chieh Hsu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
A review of anti-infective and anti-inflammatory chalcones
Zdzislawa Nowakowska
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2007)
Structural requirement of chalcones for the inhibitory activity of interleukin-5
Hyun-Mo Yang et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2007)
Lapatinib plus capecitabine for HER2-positive advanced breast cancer
Charles E. Geyer et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Impact of EGFR point mutations on the sensitivity to gefitinib: Insights from comparative structural analyses and molecular dynamics simulations
Bing Liu et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2006)
Heme oxygenase 1 mediates anti-inflammatory effects of 2′,4′ 6′-tris (methoxymethoxy) chalcone
SH Lee et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2006)
Development and testing of a general amber force field
JM Wang et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)
Structure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitor
J Stamos et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains
H Ogiso et al.
CELL (2002)
Share Paper
