Journal
MOLECULES
Volume 24, Issue 5, Pages -Publisher
MDPI
DOI: 10.3390/molecules24050830
Keywords
C-H functionalization; directing groups; amides; transition metals; catalysis
Funding
- Wenner-Gren Foundation
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Weinreb amides are a privileged, multi-functional group with well-established utility in classical synthesis. Recently, several studies have demonstrated the use of Weinreb amides as interesting substrates in transition metal-catalyzed C-H functionalization reactions. Herein, we review this part of the literature, including the metal catalysts, transformations explored so far and specific insights from mechanistic studies.
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