Journal
MOLECULES
Volume 24, Issue 3, Pages -Publisher
MDPI
DOI: 10.3390/molecules24030535
Keywords
8-amidoquinoline; iron; catalysis; water
Funding
- National Natural Science Foundation of China [21472128]
- Sichuan Science and Technology Program [2018JY560]
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A simple protocol of iron(III)-catalyzed halogenation of 8-amidoquinolines in water under mild conditions was developed, affording the 5-halogenlated products in good to excellent yields up to 98%. The reaction mechanism most likely involves a single-electron transfer (SET) process.
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