Journal
MOLECULES
Volume 24, Issue 3, Pages -Publisher
MDPI
DOI: 10.3390/molecules24030519
Keywords
biosensors; biophotonics; integrated optical sensors; aptamers; biomaterials; optical sensor; silicon photonics; ring resonators; lab-on-a-chip
Funding
- European Regional Development Fund [10.13039/501100008530]
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Recent developments in optical biosensors based on integrated photonic devices are reviewed with a special emphasis on silicon-on-insulator ring resonators. The review is mainly devoted to the following aspects: (1) Principles of sensing mechanism, (2) sensor design, (3) biofunctionalization procedures for specific molecule detection and (4) system integration and measurement set-ups. The inherent challenges of implementing photonics-based biosensors to meet specific requirements of applications in medicine, food analysis, and environmental monitoring are discussed.
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