4.5 Article

Complete genome sequence of Janthinobacterium sp. B9-8, a violacein-producing bacterium isolated from low-temperature sewage

Journal

MICROBIAL PATHOGENESIS
Volume 128, Issue -, Pages 178-183

Publisher

ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.micpath.2019.01.003

Keywords

Janthinobacterium sp.; Complete genome sequencing; Violacein; Antibiotic

Funding

  1. National Natural Science Foundation of China [21776136, 21606129, U1603112]
  2. Program for Innovative Research Teams in Universities of Jiangsu Province
  3. Jiangsu Synergetic Innovation Center for Advanced Bio-Manufacture [XTC1810]

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Janthinobacterium sp. B9-8, isolated from low temperature-sewage in Xinjiang, China, is capable of producing violacein, a promising antibiotic. Here we report the genome sequence of B9-8, which consist of 4,726,850 bp with a G + C content of 48.72%. The violacein biosynthesis gene cluster vioABCDE was identified and analyzed based on the genomic data, which revealed relatively low query coverage (3-44%) and identity (66-87%) with existing strains. Janthinobacterium sp. B9-8 grew fast and reached a high cell density and violacein content within 24 h at 25 degrees C. The availability of this genome sequence will greatly benefit the industrial production of violacein and facilitate supplementary studies on the mechanism for violacein biosynthesis.

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