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Impact of Different Types of Diet on Gut Microbiota Profiles and Cancer Prevention and Treatment

Journal

MEDICINA-LITHUANIA
Volume 55, Issue 4, Pages -

Publisher

MDPI
DOI: 10.3390/medicina55040084

Keywords

cancer; calorie restriction; ketogenic diet; Mediterranean diet; microbiota

Funding

  1. Italian Ministry of Health through the Division of Gastroenterology IRCCS Casa Sollievo della Sofferenza Hospital [RC1703GA31, RC1803GA30]
  2. 5x1000 voluntary contributions

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Diet is frequently considered as a food regimen focused on weight loss, while it is actually the sum of food consumed by the organism. Western diets, modern lifestyle, sedentary behaviors, smoking habits, and drug consumption have led to a significant reduction of gut microbial diversity, which is linked to many non-communicable diseases (NCDs). The latter kill 40 million people each year, equivalent to more than 70% of all deaths globally. Among NCDs, tumors play a major role, being responsible for 29% of deaths from NCDs. A link between diet, microbiota, and cancer prevention and treatment has recently been unveiled, underlining the importance of a new food culture based on limiting dietary surplus and on preferring healthier foods. Here, we review the effects of some of the most popular cancer-specific diets on microbiota composition and their potential impact on cancer prevention and treatment.

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