Journal
LANGMUIR
Volume 35, Issue 14, Pages 5050-5053Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.langmuir.8b04272
Keywords
-
Funding
- Shanghai Science and Technology Committee (STCSM) [18490740500]
- National Science Foundation of China [21722502]
- 1000 Youth Talents Plan
Ask authors/readers for more resources
We report a triplex-based DNA device coupled with molybdenum disulfide (MoS2) nanosheets for use as a pH-sensing platform. The device transitions from a duplex state at pH 8 to a triplex state at pH 5. The interaction of the device with MoS2 nanosheets in the two states is read out as a fluorescence signal from a pH-insensitive dye attached to the device. We characterized the operation of the DNA device on MoS2 nanosheets, analyzed the pH response, and tested the reversibility of the system. Our strategy can lead to the creation of a suite of biosensors where the sensing element is a triplex DNA device and the signal response is modulated by inorganic nanomaterials.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
