Journal
ANALYTICA CHIMICA ACTA
Volume 944, Issue -, Pages 51-56Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.aca.2016.09.023
Keywords
Resorcinol; Dopamine detection; Azamonardine; Turn-on fluorescence
Categories
Funding
- Natural Science Foundation of China [21264013, 21364010]
Ask authors/readers for more resources
A simple, fast and low-cost method for dopamine (DA) detection based on turn-on fluorescence using resorcinol is developed. The rapid reaction between resorcinol and DA allows the detection to be performed within 5 min, and the reaction product (azamonardine) with high quantum yield generates strong fluorescence signal for sensitive optical detection. The detection exhibits a high sensitivity to DA with a wide linear range of 10 nM-20 mu M and the limit of detection is estimated to be 1.8 nM (S/N = 3). This approach has been successfully applied to determine DA concentrations in human urine samples with satisfactory quantitative recovery of 97.84%-103.50%, which shows great potential in clinical diagnosis. (C) 2016 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available