4.6 Review

Recent progress in chromogenic and fluorogenic chemosensors for hypochlorous acid

Journal

ANALYST
Volume 141, Issue 6, Pages 1859-1873

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c6an00158k

Keywords

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Funding

  1. National Natural Science Foundation of China [21102086, 21472118]
  2. Shanxi Province Science Foundation for Youths [2012021009-4, 2013011011-1]
  3. Shanxi Province Foundation for Returnee [2012-007]
  4. Taiyuan Technology Star Special [12024703]
  5. Program for the Top Young and Middle-aged Innovative Talents of Higher Learning Institutions of Shanxi [2013802]
  6. Talents Support Program of Shanxi Province [2014401]
  7. CAS Key Laboratory of Analytical Chemistry for Living Biosystems Open Foundation [ACL201304]
  8. National Institutes of Health [R15EB016870]
  9. NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING [R15EB016870] Funding Source: NIH RePORTER

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Due to the biological and industrial importance of hypochlorous acid, the development of optical probes for HOCl has been an active research area. Hypochlorous acid and hypochlorite can oxidize electron-rich analytes with accompanying changes in molecular sensor spectroscopic profiles. Probes for such processes may monitor HOCl levels in the environment or in an organism and via bio-labeling or bioimaging techniques. This review summarizes recent developments in the area of chromogenic and fluorogenic chemosensors for HOCl.

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