Journal
ANALYST
Volume 141, Issue 13, Pages 3997-4000Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6an00795c
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Funding
- National Natural Science Foundation of China [81503086]
- Tianjin University of Science Technology [20140520]
- 1000 Talents Plan of Tianjin
- Foundation of Key Laboratory of Industrial Fermentation Microbiology of Ministry of Education
- Tianjin Key Lab of Industrial Microbiology [2015IM106]
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We have constructed a 'turn-off' and label free bio-sensor using a DNAzyme molecule. This facile bio-sensor is capable of selective detection of mercuric ions with a high sensitivity and satisfactory dynamic range. More importantly, it is able to generate both fluorescent and colourimetric signals for detection. This dual-channel bio-sensor is expected to afford high detection confidence and overcome false-positive readout especially when assaying complex biological samples.
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