Journal
JOURNAL OF THE CHINESE CHEMICAL SOCIETY
Volume 66, Issue 7, Pages 769-774Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/jccs.201800349
Keywords
alkyl isocyanides; arylaldehydes; isoquinoline; Meldrum's acid; phthalhydrazide-functionalized MCM-41
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Funding
- Yasouj University, Yasouj, Iran
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We present a study on the synthesis, characterization, and application of phthalhydrazide-functionalized MCM-41 (P-MCM-41) as a novel and efficient heterogeneous basic catalyst. The described catalyst was fully characterized via various techniques such as scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy dispersive X-ray (EDX), X-ray diffraction (XRD), and Fourier transform infrared (FT-IR). P-MCM-41 efficiently catalyzed the four-component reaction of arylaldehydes, Meldrum's acid, alkyl isocyanides, and isoquinoline in CHCl3 to prepare pyrrolo[2,1-a]isoquinolines in good yields.
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