4.8 Article

Alkenyl Exchange of Allylamines via Nickel(0)-Catalyzed C-C Bond Cleavage

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 141, Issue 7, Pages 2889-2893

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jacs.8b13251

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Funding

  1. National Natural Science Foundation of China [21790332, 21532003]
  2. 111 project [B06005]
  3. Ministry of Education of China

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A functional group exchange reaction between allylamines and alkenes via nickel -catalyzed C-C bond cleavage and formation was developed. This reaction provides a novel protocol, which does not require the use of unstable imine substrates, for the synthesis of allylamines, which are widely used in the production of fine chemicals, pharmaceuticals, and agrochemicals.

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