Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 84, Issue 6, Pages 3735-3740Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.9b00324
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Funding
- NSF [CHE-1664961]
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A palladium-catalyzed cross-coupling of aryl chlorides/bromides with TMSCF2H is described. Two different catalysts, Pd(dba)(2)/BrettPhos and Pd((PBu3)-Bu-t)(2), are demonstrated and provide a variety of difluoromethylated arenes in good yields.
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