Related references
Note: Only part of the references are listed.3D tumor spheroids as in vitro models to mimic in vivo human solid tumors resistance to therapeutic drugs
Ana S. Nunes et al.
BIOTECHNOLOGY AND BIOENGINEERING (2019)
CDK4/6 Inhibition Augments Antitumor Immunity by Enhancing T-cell Activation
Jiehui Deng et al.
CANCER DISCOVERY (2018)
Deconstruction of a Metastatic Tumor Microenvironment Reveals a Common Matrix Response in Human Cancers
Oliver M. T. Pearce et al.
CANCER DISCOVERY (2018)
Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids
Russell W. Jenkins et al.
CANCER DISCOVERY (2018)
Design of spherically structured 3D in vitro tumor models -Advances and prospects
L. P. Ferreira et al.
ACTA BIOMATERIALIA (2018)
Pathologic features of response to neoadjuvant anti-PD-1 in resected non-small-cell lung carcinoma: a proposal for quantitative immune-related pathologic response criteria (irPRC)
T. R. Cottrell et al.
ANNALS OF ONCOLOGY (2018)
3D-3-culture: A tool to unveil macrophage plasticity in the tumour microenvironment
Sofia P. Rebelo et al.
BIOMATERIALS (2018)
Fibroblast Heterogeneity and Immunosuppressive Environment in Human Breast Cancer
Ana Costa et al.
CANCER CELL (2018)
Cancer-Stimulated CAFs Enhance Monocyte Differentiation and Protumoral TAM Activation via IL6 and GM-CSF Secretion
Haaglim Cho et al.
CLINICAL CANCER RESEARCH (2018)
Humanized mice in studying efficacy and mechanisms of PD-1-targeted cancer immunotherapy
Minan Wang et al.
FASEB JOURNAL (2018)
Inhibiting YAP expression suppresses pancreatic cancer progression by disrupting tumor-stromal interactions
Zhengdong Jiang et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2018)
Micropassage-embedding composite hydrogel fibers enable quantitative evaluation of cancer cell invasion under 3D coculture conditions
Manami Sugimoto et al.
LAB ON A CHIP (2018)
International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study
Franck Pages et al.
LANCET (2018)
TGFβ drives immune evasion in genetically reconstituted colon cancer metastasis
Daniele V. F. Tauriello et al.
NATURE (2018)
Understanding the tumor immune microenvironment (TIME) for effective therapy
Mikhail Binnewies et al.
NATURE MEDICINE (2018)
hMENA isoforms impact NSCLC patient outcome through fibronectin/β1 integrin axis
Francesca Di Modugno et al.
ONCOGENE (2018)
Macrophages impede CD8 T cells from reaching tumor cells and limit the efficacy of anti-PD-1 treatment
Elisa Peranzoni et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Cancer-associated fibroblasts induce PDL1+neutrophils through the IL6-STAT3 pathway that foster immune suppression in hepatocellular carcinoma
Yusheng Cheng et al.
CELL DEATH & DISEASE (2018)
Microfluidic Tumor-Vascular Model to Study Breast Cancer Cell Invasion and Intravasation
Supriya Nagaraju et al.
ADVANCED HEALTHCARE MATERIALS (2018)
Engineering a Tumor Microenvironment-Mimetic Niche for Tissue Regeneration with Xenogeneic Cancer Cells
Zhenzhen Wang et al.
ADVANCED SCIENCE (2018)
Alteration of the Antitumor immune Response by Cancer-Associated Fibroblasts
Linda Ziani et al.
FRONTIERS IN IMMUNOLOGY (2018)
Hypoxia-Driven immunosuppressive Metabolites in the Tumor Microenvironment: New Approaches for Combinational immunotherapy
Yiliang Li et al.
FRONTIERS IN IMMUNOLOGY (2018)
Three Dimensional Mixed-Cell Spheroids Mimic Stroma-Mediated Chemoresistance and Invasive Migration in hepatocellular carcinoma
Iftikhar Ali Khawar et al.
NEOPLASIA (2018)
Development of PD-1 and PD-L1 inhibitors as a form of cancer immunotherapy: a comprehensive review of registration trials and future considerations
Jun Gong et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2018)
Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids
Krijn K. Dijkstra et al.
CELL (2018)
3D microfluidic ex vivo culture of organotypic tumor spheroids to model immune checkpoint blockade
Amir R. Aref et al.
LAB ON A CHIP (2018)
TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells
Sanjeev Mariathasan et al.
NATURE (2018)
Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response
Peng Jiang et al.
NATURE MEDICINE (2018)
Fundamental Mechanisms of Immune Checkpoint Blockade Therapy
Spencer C. Wei et al.
CANCER DISCOVERY (2018)
A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade
Livnat Jerby-Arnon et al.
CELL (2018)
Evolution of Metastases in Space and Time under Immune Selection
Mihaela Angelova et al.
CELL (2018)
Targeted hypoxia reduction restores T cell infiltration and sensitizes prostate cancer to immunotherapy
Priyamvada Jayaprakash et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Mouse Models for Cancer Immunotherapy Research
Brian Olson et al.
CANCER DISCOVERY (2018)
Tumor-like lung cancer model based on 3D bioprinting
Xiong Wang et al.
3 BIOTECH (2018)
Background-deflection Brillouin microscopy reveals altered biomechanics of intracellular stress granules by ALS protein FUS
Giuseppe Antonacci et al.
COMMUNICATIONS BIOLOGY (2018)
A novel three-dimensional heterotypic spheroid model for the assessment of the activity of cancer immunotherapy agents
Sylvia Herter et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2017)
Single cell analysis of human tissues and solid tumors with mass cytometry
Nalin Leelatian et al.
CYTOMETRY PART B-CLINICAL CYTOMETRY (2017)
PEG-fibrinogen hydrogels for three-dimensional breast cancer cell culture
Shantanu Pradhan et al.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2017)
Organoids: A historical perspective of thinking in three dimensions
Marina Simian et al.
JOURNAL OF CELL BIOLOGY (2017)
Yes-associated protein mediates immune reprogramming in pancreatic ductal adenocarcinoma
S. Murakami et al.
ONCOGENE (2017)
Induction of hypoxia and necrosis in multicellular tumor spheroids is associated with resistance to chemotherapy treatment
Silvio Daester et al.
ONCOTARGET (2017)
Modeling tumor cell adaptations to hypoxia in multicellular tumor spheroids
Stephen Riffle et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2017)
Tumour-on-a-chip: microfluidic models of tumour morphology, growth and microenvironment
Hsieh-Fu Tsai et al.
JOURNAL OF THE ROYAL SOCIETY INTERFACE (2017)
Elements of cancer immunity and the cancer-immune set point
Daniel S. Chen et al.
NATURE (2017)
The emergence of optical elastography in biomedicine
Brendan F. Kennedy et al.
NATURE PHOTONICS (2017)
Cellular adaptation to biomechanical stress across length scales in tissue homeostasis and disease
Penney M. Gilbert et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2017)
A Biomimetic Microfluidic Tumor Microenvironment Platform Mimicking the EPR Effect for Rapid Screening of Drug Delivery Systems
Yuan Tang et al.
SCIENTIFIC REPORTS (2017)
Tumor-Associated Tertiary Lymphoid Structures: Gene-Expression Profiling and Their Bioengineering
Genyuan Zhu et al.
FRONTIERS IN IMMUNOLOGY (2017)
3D Microfluidic model for evaluating immunotherapy efficacy by tracking dendritic cell behaviour toward tumor cells
Stefania Parlato et al.
SCIENTIFIC REPORTS (2017)
PDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models
Terrence F. Meehan et al.
CANCER RESEARCH (2017)
De novo induction of intratumoral lymphoid structures and vessel normalization enhances immunotherapy in resistant tumors
Anna Johansson-Percival et al.
NATURE IMMUNOLOGY (2017)
Molecular Pathways: Oncologic Pathways and Their Role in T-cell Exclusion and Immune Evasion-A New Role for the AXL Receptor Tyrosine Kinase
Todd A. Aguilera et al.
CLINICAL CANCER RESEARCH (2017)
The emerging role of ECM crosslinking in T cell mobility as a hallmark of immunosenescence in humans
Jean-Francois Moreau et al.
AGEING RESEARCH REVIEWS (2017)
Bioprinting for vascular and vascularized tissue biofabrication
Pallab Datta et al.
ACTA BIOMATERIALIA (2017)
The bioink: A comprehensive review on bioprintable materials
Monika Hospodiuk et al.
BIOTECHNOLOGY ADVANCES (2017)
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
Padmanee Sharma et al.
CELL (2017)
Microfl uidic Bioprinting of Heterogeneous 3D Tissue Constructs Using Low-Viscosity Bioink
Cristina Colosi et al.
ADVANCED MATERIALS (2016)
3D Bioprinting a Cell-Laden Bone Matrix for Breast Cancer Metastasis Study
Xuan Zhou et al.
ACS APPLIED MATERIALS & INTERFACES (2016)
A comprehensive review on droplet-based bioprinting: Past, present and future
Hemanth Gudapati et al.
BIOMATERIALS (2016)
Current advances and future perspectives in extrusion-based bioprinting
Ibrahim T. Ozbolat et al.
BIOMATERIALS (2016)
Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma
Willy Hugo et al.
CELL (2016)
Fibroblast activation in cancer: when seed fertilizes soil
Sanya-Eduarda Kuzet et al.
CELL AND TISSUE RESEARCH (2016)
Organoid-on-a-chip and body-on-a-chip systems for drug screening and disease modeling
Aleksander Skardal et al.
DRUG DISCOVERY TODAY (2016)
Resistance Mechanisms to Immune-Checkpoint Blockade in Cancer: Tumor-Intrinsic and -Extrinsic Factors
Jonathan M. Pitt et al.
IMMUNITY (2016)
Trends and advances in tumor immunology and lung cancer immunotherapy
Mohanad Aldarouish et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2016)
Chemotaxis-driven assembly of endothelial barrier in a tumor-on-a-chip platform
Aereas Aung et al.
LAB ON A CHIP (2016)
Overcoming resistance to checkpoint blockade therapy by targeting PI3Kγ in myeloid cells
Olivier De Henau et al.
NATURE (2016)
Targeting focal adhesion kinase renders pancreatic cancers responsive to checkpoint immunotherapy
Hong Jiang et al.
NATURE MEDICINE (2016)
Forcing throuch Tumor Metastasis: The Interplay between Tissue Rigidity and Epithelial-Mesenchymal Transition
Spencer C. Wei et al.
TRENDS IN CELL BIOLOGY (2016)
Design and Printing Strategies in 3D Bioprinting of Cell-Hydrogels: A Review
Jia Min Lee et al.
ADVANCED HEALTHCARE MATERIALS (2016)
Timing of CSF-1/CSF-1R signaling blockade is critical to improving responses to CTLA-4 based immunotherapy
Rikke B. Holmgaard et al.
ONCOIMMUNOLOGY (2016)
Computer-aided multiple-head 3D printing system for printing of heterogeneous organ/tissue constructs
Jin Woo Jung et al.
SCIENTIFIC REPORTS (2016)
Biomechanics of subcellular structures by non-invasive Brillouin microscopy
Giuseppe Antonacci et al.
SCIENTIFIC REPORTS (2016)
Activated hepatic stellate cells play pivotal roles in hepatocellular carcinoma cell chemoresistance and migration in multicellular tumor spheroids
Yeonhwa Song et al.
SCIENTIFIC REPORTS (2016)
The biology and function of fibroblasts in cancer
Raghu Kalluri
NATURE REVIEWS CANCER (2016)
Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
Chih-Hao Chang et al.
CELL (2015)
Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity
Santiago Zelenay et al.
CELL (2015)
The regulation of immune cell trafficking by the extracellular matrix
Rupert Hallmann et al.
CURRENT OPINION IN CELL BIOLOGY (2015)
Recent developments in multiplexing techniques for immunohistochemistry
Angela R. Dixon et al.
EXPERT REVIEW OF MOLECULAR DIAGNOSTICS (2015)
Peritumoural neutrophils negatively regulate adaptive immunity via the PD-L1/PD-1 signalling pathway in hepatocellular carcinoma
Gaixia He et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2015)
Quantification of plaque stiffness by Brillouin microscopy in experimental thin cap fibroatheroma
Giuseppe Antonacci et al.
JOURNAL OF THE ROYAL SOCIETY INTERFACE (2015)
Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity
Stefani Spranger et al.
NATURE (2015)
Noncontact three-dimensional mapping of intracellular hydromechanical properties by Brillouin microscopy
Giuliano Scarcelli et al.
NATURE METHODS (2015)
T cell exclusion, immune privilege, and the tumor microenvironment
Johanna A. Joyce et al.
SCIENCE (2015)
Bioprinting for cancer research
Stephanie Knowlton et al.
TRENDS IN BIOTECHNOLOGY (2015)
Notes on stochastic (bio)-logic gates: computing with allosteric cooperativity
Elena Agliari et al.
SCIENTIFIC REPORTS (2015)
Real-time imaging of resident T cells in human lung and ovarian carcinomas reveals how different tumor microenvironments control T lymphocyte migration
Houcine Bougherara et al.
FRONTIERS IN IMMUNOLOGY (2015)
Human 3D vascularized organotypic microfluidic assays to study breast cancer cell extravasation
Jessie S. Jeon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Cell encapsulation via microtechnologies
AhRan Rang et al.
BIOMATERIALS (2014)
3D printing of biomimetic microstructures for cancer cell migration
Tina Qing Huang et al.
BIOMEDICAL MICRODEVICES (2014)
Prevailing Role of Contact Guidance in Intrastromal T-cell Trapping in Human Pancreatic Cancer
Natalie Hartmann et al.
CLINICAL CANCER RESEARCH (2014)
The extracellular matrix modulates the hallmarks of cancer
Michael W. Pickup et al.
EMBO REPORTS (2014)
Fibroblast heterogeneity in the cancer wound
Daniel Oehlund et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
A Novel Feeder-Free Culture System for Expansion of Mouse Spermatogonial Stem Cells
Na Young Choi et al.
MOLECULES AND CELLS (2014)
Extracellular matrix stiffness and composition jointly regulate the induction of malignant phenotypes in mammary epithelium
Ovijit Chaudhuri et al.
NATURE MATERIALS (2014)
Cellular Localization, Invasion, and Turnover Are Differently Influenced by Healthy and Tumor-Derived Extracellular Matrix
Luca Genovese et al.
TISSUE ENGINEERING PART A (2014)
Tertiary lymphoid structures in cancer and beyond
Marie-Caroline Dieu-Nosjean et al.
TRENDS IN IMMUNOLOGY (2014)
Three-dimensional printing of Hela cells for cervical tumor model in vitro
Yu Zhao et al.
BIOFABRICATION (2014)
The Carcinoma-Associated Fibroblast Expressing Fibroblast Activation Protein and Escape from Immune Surveillance
Douglas T. Fearon
CANCER IMMUNOLOGY RESEARCH (2014)
Spectral broadening in Brillouin imaging
Giuseppe Antonacci et al.
APPLIED PHYSICS LETTERS (2013)
Three-Dimensional Scaffolds to Evaluate Tumor Associated Fibroblast-Mediated Suppression of Breast Tumor Specific T Cells
Vy Phan-Lai et al.
BIOMACROMOLECULES (2013)
Immune-suppressive properties of the tumor microenvironment
Juergen C. Becker et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2013)
Pancreatic Cancer-Associated Stellate Cells Promote Differentiation of Myeloid-Derived Suppressor Cells in a STAT3-Dependent Manner
Thomas A. Mace et al.
CANCER RESEARCH (2013)
Targeting CD73 Enhances the Antitumor Activity of Anti-PD-1 and Anti-CTLA-4 mAbs
Bertrand Allard et al.
CLINICAL CANCER RESEARCH (2013)
Matrigel supports neural, melanocytic and chondrogenic differentiation of trunk neural crest cells
Ana B. Ramos-Hryb et al.
INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY (2013)
Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force
Katarina Wolf et al.
JOURNAL OF CELL BIOLOGY (2013)
Cross talk between cancer and immune cells: exploring complex dynamics in a microfluidic environment
Luca Businaro et al.
LAB ON A CHIP (2013)
DNA nanospheres with microfluidics: a promising platform for cancer diagnosis?
Z. Hugh Fan et al.
NANOMEDICINE (2013)
Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts
Fernando Calvo et al.
NATURE CELL BIOLOGY (2013)
CSF-1R inhibition alters macrophage polarization and blocks glioma progression
Stephanie M. Pyonteck et al.
NATURE MEDICINE (2013)
In Vitro Model of Tumor Cell Extravasation
Jessie S. Jeon et al.
PLOS ONE (2013)
Flow induces epithelial-mesenchymal transition, cellular heterogeneity and biomarker modulation in 3D ovarian cancer nodules
Imran Rizvi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
The tumor microenvironment and strategies to improve drug distribution
Jasdeep K. Saggar et al.
FRONTIERS IN ONCOLOGY (2013)
Matrix architecture defines the preferential localization and migration of T cells into the stroma of human lung tumors
Helene Salmon et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Cell-Intrinsic Abrogation of TGF-β Signaling Delays but Does Not Prevent Dysfunction of Self/Tumor-Specific CD8 T Cells in a Murine Model of Autochthonous Prostate Cancer
Cassie K. Chou et al.
JOURNAL OF IMMUNOLOGY (2012)
A microfluidic-based device for study of transendothelial invasion of tumor aggregates in realtime
Qian Zhang et al.
LAB ON A CHIP (2012)
CD73: a potent suppressor of antitumor immune responses
Paul. A. Beavis et al.
TRENDS IN IMMUNOLOGY (2012)
3D Porous Chitosan-Alginate Scaffolds: A New Matrix for Studying Prostate Cancer Cell-Lymphocyte Interactions In Vitro
Stephen J. Florczyk et al.
ADVANCED HEALTHCARE MATERIALS (2012)
Multiple uses of basement membrane-like matrix BME/Matrigel) in vitro and in vivo with cancer cells
Gabriel Benton et al.
INTERNATIONAL JOURNAL OF CANCER (2011)
Role of YAP/TAZ in mechanotransduction
Sirio Dupont et al.
NATURE (2011)
Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression
Mina J. Bissell et al.
NATURE MEDICINE (2011)
Extracellular Matrix Degradation and Remodeling in Development and Disease
Pengfei Lu et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2011)
3D tumour models: novel in vitro approaches to cancer studies
Agata Nyga et al.
JOURNAL OF CELL COMMUNICATION AND SIGNALING (2011)
Dense type I collagen matrices that support cellular remodeling and microfabrication for studies of tumor angiogenesis and vasculogenesis in vitro
Valerie L. Cross et al.
BIOMATERIALS (2010)
Bioengineered 3D platform to explore cell-ECM interactions and drug resistance of epithelial ovarian cancer cells
Daniela Loessner et al.
BIOMATERIALS (2010)
Carcinoma-associated fibroblasts promoted tumor spheroid invasion on a microfluidic 3D co-culture device
Tingjiao Liu et al.
LAB ON A CHIP (2010)
Preclinical model of organotypic culture for pharmacodynamic profiling of human tumors
Valentina Vaira et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Autocrine TGF-β and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts
Yasushi Kojima et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Matrigel: A complex protein mixture required for optimal growth of cell culture
Chris S. Hughes et al.
PROTEOMICS (2010)
Laser-based direct-write techniques for cell printing
Nathan R. Schiele et al.
BIOFABRICATION (2010)
Particle-Tracking Microrheology of Living Cells: Principles and Applications
Denis Wirtz
Annual Review of Biophysics (2009)
Microfluidic system for formation of PC-3 prostate cancer co-culture spheroids
Amy Y. Hsiao et al.
BIOMATERIALS (2009)
The Mechanical Rigidity of the Extracellular Matrix Regulates the Structure, Motility, and Proliferation of Glioma Cells
Theresa A. Ulrich et al.
CANCER RESEARCH (2009)
Optical tweezers for single cells
Hu Zhang et al.
JOURNAL OF THE ROYAL SOCIETY INTERFACE (2008)
Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion
Katarina Wolf et al.
NATURE CELL BIOLOGY (2007)
Atomic force microscopy probing of cell elasticity
Tatyana G. Kuznetsova et al.
MICRON (2007)
Type, density, and location of immune cells within human colorectal tumors predict clinical outcome
Jerom Galon et al.
SCIENCE (2006)
Tensional homeostasis and the malignant phenotype
MJ Paszek et al.
CANCER CELL (2005)
Elastic Behavior of cross-linked and bundled actin networks
ML Gardel et al.
SCIENCE (2004)
Scaffolds for tissue fabrication
Peter X. Ma
MATERIALS TODAY (2004)
Cells lying on a bed of microneedles: An approach to isolate mechanical force
JL Tan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer
L Zhang et al.
NEW ENGLAND JOURNAL OF MEDICINE (2003)
Cancer immunoediting: from immunosurveillance to tumor escape
GP Dunn et al.
NATURE IMMUNOLOGY (2002)
Magnetic resonance elastography: Non-invasive mapping of tissue elasticity
A Manduca et al.
MEDICAL IMAGE ANALYSIS (2001)
Reprograming T cells: the role of extracellular matrix in coordination of T cell activation and migration
ML Dustin et al.
CURRENT OPINION IN IMMUNOLOGY (2001)
Micropipette aspiration of living cells
RM Hochmuth
JOURNAL OF BIOMECHANICS (2000)
Share Paper
